Listar Producción Científica por autor "f7931d4c-7d5f-451d-9bd9-4472bb894609"
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Antagonists of Growth Hormone-Releasing Hormone Inhibit the Growth of Pituitary Adenoma Cells by Hampering Oncogenic Pathways and Promoting Apoptotic Signaling
Gesmundo, Iacopo; Granato, Giuseppina; Fuentes-Fayos, Antonio C.; Álvarez, Clara V.; Diéguez, Carlos; Zatelli, Maria Chiara; Congiusta, Noemi; Banfi, Dana; Prencipe, Nunzia; Leone, Sheila; Brunetti, Luigi; Castaño, Justo P.; Luque, Raúl M.; Cai, Renzhi; Sha, Wei; Ghigo, Ezio; Schally, Andrew V.; Granata, Riccarda (MDPI, 2021)Pituitary adenomas (PAs) are intracranial tumors, often associated with excessive hormonal secretion and severe comorbidities. Some patients are resistant to medical therapies; therefore, novel treatment options are needed. ... -
Does telotristat have a role in preventing carcinoid heart disease?
Herrera-Martínez, Aura D.; Fuentes-Fayos, Antonio C.; Sánchez-Sánchez, Rafael; Montero-Hidalgo, Antonio J .; Sarmento-Cabral, André; Gálvez-Moreno, M. Ángeles; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2024)Carcinoid heart disease (CHD) is a frequent and life-threatening complication in patients with carcinoid tumors. Its clinical management is challenging is some cases since serotonin-induced valve fibrosis leads to heart ... -
Identification of Novel Markers and Molecular Mechanisms with Diagnostic, Prognostic, and Therapeutic Potential in Brain Tumors
Fuentes-Fayos, Antonio C. (Universidad de Córdoba, UCOPress, 2022)Primary brain tumors represent a highly variable and heterogeneous group of neoplasms (~150 different types) that includes non-malignant and malignant tumors. The most frequent malignant brain tumors are gliomas (representing ... -
PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing
López Cánovas, Juan Luis; Hermán Sánchez, Natalia; Río Moreno, Mercedes del; Fuentes-Fayos, Antonio C.; Lara López, Araceli; Sánchez-Frías, Marina; Amado-Torres, Víctor; Ciria, Rubén; Briceño Delgado, Francisco Javier; Mata, Manuel de la; Castaño, Justo P.; Rodríguez-Perálvarez, Manuel; Luque, Raúl M.; Gahete Ortiz, Manuel D. (Springer Nature, 2023)Hepatocellular carcinoma (HCC) pathogenesis is associated with alterations in splicing machinery components (spliceosome and splicing factors) and aberrant expression of oncogenic splice variants. We aimed to analyze the ... -
Somatostatin Receptor Splicing Variant sst5TMD4 Overexpression in Glioblastoma Is Associated with Poor Survival, Increased Aggressiveness Features and Somatostatin Analogs Resistance
Fuentes-Fayos, Antonio C.; G‐García, Miguel E; Pérez Gómez, J.M.; Peel, Annabel; Blanco‐Acevedo, Cristóbal; Solivera, Juan; Ibáñez-Costa, Alejandro; Gahete Ortiz, Manuel D.; Castaño, Justo P.; Luque, Raúl M. (MDPI, 2022)Glioblastoma (GBM) is the most malignant and lethal brain tumor. Current standard treatment consists of surgery followed by radiotherapy/chemotherapy; however, this is only a palliative approach with a mean post-operative ...