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Molecular, cellular and endocrine-metabolic factors involved in the pathological interaction between obesity and prostate cancer: Therapeutic role of metformin
(Universidad de Córdoba, UCOPress, 2017)
La próstata es una glándula exocrina con forma oval, localizada entre la vejiga y el pene y con el tamaño de una nuez. Esta glándula representa un órgano importante dentro de los sistemas urinarios y reproductivos ya que ...
Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition
(Blackwell Publishing, 2011)
Much attention has been drawn to the possible involvement of hypothalamic inflammation in the pathogenesis of metabolic disorders, especially in response to a high-fat diet. Microglia, the macrophages of the central nervous ...
Role of splicing process alterations in the appearance of endocrine-metabolic diseases and tumor pathologies
(Universidad de Córdoba, UCOPress, 2019)
Global human health is currently threatened by highly prevalent diseases such as obesity, diabetes and cancer. A common hallmark shared by these endocrine-metabolic and tumor diseases is the consistent alteration of the ...
Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue
(Nature Research, 2017)
During their lifetime, females are subjected to different nutritional and hormonal factors that could increase the risk of obesity and associated comorbidities. From early postnatal periods until the postmenopausal phase, ...
Equation Córdoba: A Simplified Method for Estimation of Body Fat (ECORE-BF)
(MDPI, 2019)
Background: Many methods for measuring body fat have been developed, but applications in clinical settings are limited. For this reason, researchers have tried to identify different formulas for its estimation but most of ...
Google Trends on Obesity, Smoking and Alcoholism: Global and Country-Specific Interest
(MDPI, 2021)
Unhealthy habits or lifestyles, such as obesity, smoking, and alcohol consumption, are involved in the development of non-communicable diseases. The aim of this study was to analyze different communities’ interest in seeking ...
An Approach to Early Detection of Metabolic Syndrome through Non-Invasive Methods in Obese Children
(MDPI, 2020)
Background: Metabolic Syndrome (MetS) has a high prevalence in children, and its presence increases in those with a high BMI. This fact confirms the need for early detection to avoid the development of other comorbidities. ...
Ibero–American Consensus on Low- and No-Calorie Sweeteners: Safety, Nutritional Aspects and Benefits in Food and Beverages
(MDPI, 2018)
International scientific experts in food, nutrition, dietetics, endocrinology, physical activity,
paediatrics, nursing, toxicology and public health met in Lisbon on 2–4 July 2017 to develop
a Consensus on the use of ...
Flavonoid Phloretin Inhibits Adipogenesis and Increases OPG Expression in Adipocytes Derived from Human Bone-Marrow Mesenchymal Stromal-Cells
(MDPI, 2021)
Phloretin (a flavonoid abundant in apple), has antioxidant, anti-inflammatory, and glucose-transporter inhibitory properties. Thus, it has interesting pharmacological and nutraceutical potential. Bone-marrow mesenchymal ...
Mediators of the cellular response to the development of obesity and metabolic disease
(Universidad de Córdoba, UCOPress, 2021)
Obesity is the pandemic of the 21st century. Overall, about 15% of the world’s adult population is obese, and if the rising trend continues, it is estimated that global prevalence reaches 20% by 2025. Obesity poses a major ...