Listar OpenAIRE (Open Access Infrastructure for Research in Europe) por autor "3e256b3a-72ea-464d-9d26-293fafbf6b9a"
Mostrando ítems 1-2 de 2
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In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation
Martínez-Moreno, Julio M.; Muñoz-Castañeda, Juan R.; Herencia, Carmen; Montes de Oca, Addy; Estepa Nieto, José Carlos; Canalejo, Rocío; Rodríguez-Ortiz, Maria E.; Aguilera Tejero, Escolástico; Canalejo, Antonio; Rodríguez, Mariano; Almadén Peña, Yolanda; Pérez-Martínez, Pablo (American Journal of Physiology, 2012)The present study investigates the differential effect of two vitamin D receptor agonists, calcitriol and paricalcitol, on human aortic smooth muscle cells calcification in vitro. Human vascular smooth muscle cells were ... -
TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
Guerrero Pavón, Fátima; Herencia, Carmen; Almadén Peña, Yolanda; Martínez-Moreno, Julio M.; Montes de Oca, Addy; Rodríguez-Ortiz, Maria E.; Díaz Tocados, Juan Manuel; Florio, Mónica; López, Ignacio; Richards, William G.; Rodríguez Portillo, Mariano; Aguilera Tejero, Escolástico; Muñoz-Castañeda, Juan R. (Public Library of Science, 2014)Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ...