Listar Departamento de Anatomía y Anatomía Patológica Comparadas y Toxicología por autor "85732f3a-dafa-4276-ac6a-897901288caf"
Mostrando ítems 1-3 de 3
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Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications
Aurilio, Gaetano; Cimadamore, Alessia; Mazzucchelli, Roberta; López-Beltrán, Antonio; Verri, Elena; Scarpelli, Marina; Massari, Francesco; Cheng, Liang; Santoni, Matteo; Montironi, Rodolfo (MDPI, 2020)Around 80–90% of prostate cancer (PCa) cases are dependent on androgens at initial diagnosis; hence, androgen ablation therapy directed toward a reduction in serum androgens and the inhibition of androgen receptor (AR) is ... -
New Frontiers in Prostate Cancer Treatment: Are We Ready for Drug Combinations with Novel Agents?
Aurilio, Gaetano; Cimadamore, Alessia; Santoni, Matteo; Nolé, Franco; Scarpelli, Marina; Massari, Francesco; López-Beltrán, Antonio; Cheng, Liang; Montironi, Rodolfo (MDPI, 2020)Medical treatment for metastatic castration-resistant prostate cancer (mCRPC) patients has progressively been evolving from a nonspecific clinical approach to genomics-oriented therapies. The scientific community is in ... -
Update on Circulating Tumor Cells in Genitourinary Tumors with Focus on Prostate Cancer
Cimadamore, Alessia; Aurilio, Gaetano; Nolé, Franco; Massari, Francesco; Scarpelli, Marina; Santoni, Matteo; López-Beltrán, Antonio; Cheng, Liang; Montironi, Rodolfo (MDPI, 2020)Current developments in the treatment of genitourinary tumors underline the unmet clinical need for biomarkers to improve decision-making in a challenging clinical setting. The detection of circulating tumor cells (CTCs) ...