Listar por autor "09545833-56c9-4306-93d8-a786740fb49f"
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Acto de investidura de Lina Badimón Maestro y Álvaro Pascual-Leone como Doctores Honoris Causa por la Universidad de Córdoba. Laudatio
Túnez, Isaac (Universidad de Córdoba, 2022) -
Comparative of transcranial magnetic stimulation and other treatments in experimental autoimmune encephalomyelitis
Medina Fernández, Francisco Javier; Escribano, Begoña M.; Luque, Evelio; Caballero-Villarraso, Javier; Gómez-Chaparro, José L.; Feijóo, Montserrat; García-Maceira, Fé I.; Pascual-Leone, Álvaro; Drucker Colín, René Raúl; Túnez, Isaac (Elsevier, 2018)The effects of transcranial magnetic stimulation (TMS), natalizumab (nata), dimethyl fumarate (DMF) and dexamethasone (DEX) on clinical score and oxidative stress produced by a single dose of myelin oligodendrocyte ... -
Development of a High-Throughput Calcium Mobilization Assay for CCR6 Receptor Coupled to Hydrolase Activity Readout
Gómez-Melero, Sara; García-Maceira, Fé I.; García-Maceira, Tania; Luna-Guerrero, Verónica; Montero-Peñalvo, Gracia; Caballero-Villarraso, Javier; Túnez, Isaac; Paz-Rojas, Elier (MDPI, 2022)CCR6 is a chemokine receptor highly implicated in inflammatory diseases and could be a potential therapeutic target; however, no therapeutic agents targeting CCR6 have progressed into clinical evaluation. Development of a ... -
Effect of the combination of different therapies on oxidative stress in the experimental model of multiple sclerosis
Escribano, Begoña M.; Muñoz Jurado, Ana; Luque, Evelio; Galván, Alberto; Latorre, Manuel; Caballero-Villarraso, Javier; Giraldo, Ana I.; Agüera, Eduardo; Túnez, Isaac (IBRO, 2023)Oxidative stress is heavily involved in several pathological features of Multiple Sclerosis (MS), such as myelin destruction, axonal degeneration, and inflammation. Different therapies have been shown to reduce the oxidative ... -
EHO-85: A Multifunctional Amorphous Hydrogel for Wound Healing Containing Olea europaea Leaf Extract: Effects on Wound Microenvironment and Preclinical Evaluation
Casado-Díaz, Antonio; La Torre, Manuel; Priego-Capote, Feliciano; Verdú-Soriano, José; Lázaro-Martínez, José Luis; Rodríguez-Mañas, Leocadio; Berenguer Pérez, Miriam; Túnez, Isaac (MDPI, 2022)The prevalence of chronic wounds is increasing due to the population aging and associated pathologies, such as diabetes. These ulcers have an important socio-economic impact. Thus, it is necessary to design new products ... -
Extra-Virgin Olive Oil Modifies the Changes Induced in Non-Nervous Organs and Tissues by Experimental Autoimmune Encephalomyelitis Models
Conde, Cristina; Escribano, Begoña M.; Luque, Evelio; Feijóo, Montserrat; Caballero-Villarraso, Javier; Valdelvira, Manuel E.; Ochoa Sepúlveda, Juan J.; Lillo, Rafael; Paz, Elier; Santamaría, Abel; Agüera, Eduardo; Túnez, Isaac (MDPI, 2019)This study reveals the existence of oxidative stress (reactive oxygen species (ROS)) in non-nervous organs and tissues in multiple sclerosis (MS) by means of a model of experimental autoimmune encephalomyelitis (EAE) in ... -
Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review
Gómez-Melero, Sara; Caballero-Villarraso, Javier; Escribano, Begoña M.; Galvao-Carmona, Alejandro; Túnez, Isaac; Agüera Morales, Eduardo (MDPI, 2024)Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and ... -
Influencia de la fuerza muscular isométrica de las extremidades superiores en el estrés oxidativo en niños
Benítez Sillero, Juan de Dios; Pérez Navero, Juan Luis; Gil Campos, Mercedes; Guillén del Castillo, Manuel; Tasset, Inmaculada; Túnez, Isaac (Ramón Cantó Alcaraz, 2011)El ejercicio físico puede producir estrés oxidativo en el individuo lo que pueden condicionar el riesgo cardiovascular en niños y adolescentes. Este estudio pretende analizar el estrés oxidativo según la fuerza muscular ... -
Neuroprotective effect of S-allyl cysteine on an experimental model of multiple sclerosis: Antioxidant effects
Escribano, Begoña M.; Agüera Carmona, Eduardo; Aguilar-Luque, Macarena; Luque, Evelio; Feijóo, Montserrat; Latorre, Manuel; Giraldo, Ana I.; Galván-Jurado, A.; Caballero-Villarraso, Javier; García-Maceira, Fé I.; Santamaría, Abel; Túnez, Isaac (Elsevier, 2018)S-allyl cysteine (SAC), has shown itself to performance important activity as a neuroprotective agent. This action is prompted by antioxidative activity. The aim of this study was to evaluate the neuroprotective effect of ... -
The protective effect of extra-virgin olive oil in the experimental model of multiple sclerosis in the rat
Conde, Cristina; Escribano, Begoña M.; Luque, Evelio; Aguilar-Luque, Macarena; Feijoo, Marisa; Ochoa, J.J.; Latorre, Manuel; Giraldo, Ana I.; Lillo, Rafael; Agüera Carmona, Eduardo; Santamaría, Abel; Túnez, Isaac (Taylor & Francis, 2018)This study has evaluated the effect of EVOO (Extra-Virgin olive oil), OA (oleic acid) and HT (hydroxytyrosol) in an induced model of MS through experimental autoimmune encephalomyelitis (EAE). Dark Agouti 2-month old ... -
Transcranial Magnetic Stimulation Improves Muscle Involvement in Experimental Autoimmune Encephalomyelitis
Peña-Toledo, María Ángeles; Luque, Evelio; Ruz‐Caracuel, Ignacio; Agüera, Eduardo; Jimena Medina, Ignacio; Peña Amaro, J.; Túnez, Isaac (MDPI, 2021)Skeletal muscle is affected in experimental autoimmune encephalomyelitis (EAE), which is a model of multiple sclerosis that produces changes including muscle atrophy; histological features of neurogenic involvement, and ...