• Crohn’s Disease Increases the Mesothelial Properties of Adipocyte Progenitors in the Creeping Fat 

      Madeira, Ana; Serena, Carolina; Ejarque, Miriam; Maymó-Masip, Elsa; Millán, Mónica; Navarro-Ruiz, Carmen; Guzmán Ruiz, R.; Malagón, María M.; Espin, Eloy; Martí, Marc; Menacho, Margarita; Megía, Ana; Vendrell, Joan; Fernández-Veledo, Sonia (MDPI, 2021)
      Our understanding of the interplay between human adipose tissue and the immune system is limited. The mesothelium, an immunologically active structure, emerged as a source of visceral adipose tissue. After investigating ...
    • Experiencias en flipped learning 

      Burón, Isabel; Avendaño, S.; Cantarero, Irene; Gahete Ortiz, Manuel D.; Guzmán Ruiz, R.; Vázquez, M.J.; Luque, Rafael; Malagón, María M.; Villalba, José Manuel; Calzado Canale, Marco Antonio (UCOPress, 2018)
      El presente trabajo describe unas experiencias de innovación docente, de igual perfil y metodología, desarrolladas por un conjunto de profesores noveles participantes bajo la tutela experta de profesorado senior. El tipo ...
    • Rab18 drift in lipid droplet and endoplasmic reticulum interactions of adipocytes under obesogenic conditions 

      López-Alcalá, J.; Soler-Vázquez, M. Carmen; Tercero-Alcázar, C.; Sánchez Ceinos, Julia; Guzmán Ruiz, R.; Malagón, María M.; Gordon, Ana (MDPI, 2023)
      The adipose tissue stores excess energy in the form of neutral lipids within adipocyte lipid droplets (LDs). The correct function of LDs requires the interaction with other organelles, such as the endoplasmic reticulum ...
    • The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast 

      Arias de la Rosa, Iván; López-Montilla, María Dolores; Román-Rodríguez, Cristobal; Pérez Sánchez, Carlos; Gómez-García, Ignacio; López Medina, Eloísa Clementina; Ladehesa-Pineda, Lourdes; Ábalos-Aguilera, María del Carmen; Ruiz, Desireé; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Añón-Oñate, Isabel; Pérez-Galán, María José; Guzmán Ruiz, R.; Malagón, María M.; López-Pedrera, Ch.; Escudero Contreras, Alejandro; Collantes Estévez, Eduardo; Barbarroja, Nuria (Wiley, 2022)
      Objectives: (1) To evaluate clinical and molecular cardiovascular disease (CVD) signs and their relationship with psoriatic arthritis (PsA) features and (2) to identify a clinical patient profile susceptible to benefit ...
    • The potential role of the adipokine HMGB1 in obesity and insulin resistance. Novel effects on adipose tissue biology 

      Guzmán Ruiz, R.; Tercero-Alcázar, C.; López-Alcalá, J.; Sánchez Ceinos, Julia; Malagón, María M.; Gordon, Ana (Elsevier, 2021)
      Discovery of the adipose tissue as a major source of signaling molecules almost three decades ago set a novel physiological paradigm that paved the way for the identification of metabolic organs as endocrine organs. ...