Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 35-54 de 280
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Cannabidiol and Other Cannabinoids in Demyelinating Diseases
(MDPI, 2021)A growing body of preclinical evidence indicates that certain cannabinoids, including cannabidiol (CBD) and synthetic derivatives, may play a role in the myelinating processes and are promising small molecules to be developed ... -
Caracterización celular y molecular de la proteina neuroendocrine long coiled-coil 2 (NECC2)
(Universidad de Córdoba, Servicio de Publicaciones, 2011)Como se mencionó en la introducción del presente trabajo, estudios previos en nuestro grupo de investigación permitieron la identificación de una nueva proteína long coiled-coil específica de vertebrados a partir de un ... -
Caracterización de alteraciones metabólicas y reproductoras en modelos de manipulación nutricional y gonadal aplicada en diversas etapas del desarrollo: impacto de la obesidad sobre el eje reproductor
(Universidad de Córdoba, Servicio de Publicaciones, 2014)1. Introducción o motivación de la tesis Actualmente, la obesidad es la enfermedad metabólica más frecuente en los países desarrollados, estando asociada a la aparición de otras morbilidades, como resistencia a insulina, ... -
Caracterización de las conexiones intracelulares que definen la expansión disfuncional del tejido adiposo en obesidad
(Universidad de Córdoba, UCOPress, 2024)El tejido adiposo desempeña un papel esencial en la gestión de las reservas energéticas del organismo. Los adipocitos son las células más abundantes del tejido adiposo y constituyen su unidad funcional. Están especializados ... -
Caracterización de nuevas rutas reguladoras del metabolismo lipídico en adipocitos. Alteraciones en obesidad
(Universidad de Córdoba, UCOPress, 2020) -
Caracterización de nuevos marcadores reguladores del funcionamiento del tejido adiposo
(Universidad de Córdoba, UCOPress, 2017)El tejido adiposo blanco constituye un depósito de energía altamente dinámico, que almacena el exceso de energía en períodos de balance energético positivo y los moviliza en períodos de demanda energética (Ducharme y Bickel, ... -
Caracterización del papel del sistema NKB/NK3R en el control de la función reproductora
(Universidad de Córdoba, UCOPress, 2019) -
CCN2 Binds to Tubular Epithelial Cells in the Kidney
(MDPI, 2022)Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ... -
Ceruloplasmin and Coronary Heart Disease-A Systematic Review
(MDPI, 2020)Several studies indicate that oxidative stress might play a central role in the initiation and maintenance of cardiovascular diseases. It remains unclear whether ceruloplasmin acts as a passive marker of inflammation or ... -
Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study
(Elsevier, 2018)Background: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, ... -
Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia
(MDPI, 2020)Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ... -
Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes
(MDPI, 2021)Aims and methods: The aim of this monocentric retrospective observational study was to evaluate the 18-month safety and effectiveness of GLP-1 receptor agonist (GLP-1 RA) dulaglutide (DU) 1.5 mg/once weekly as an add-on ... -
Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer
(MDPI, 2019)Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ... -
CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
(Public Library of Science, 2014)Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in ... -
Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases
(MDPI, 2020)Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ... -
Coinfección por papilomavirus humanos y herpesvirus 6 como mecanismo patógeno en el cáncer vesical y su implicación en la progresión neoplásica
(Universidad de Córdoba, Servicio de Publicaciones, 2012)Con el fin de aportar conocimiento de índole patogenético en el cáncer de vejiga urinaria, nuestro grupo ha desarrollado varios proyectos de investigación relacionados con el papel de ciertos virus en esta neoplasia. ... -
Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells
(MDPI, 2021)A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower incidence and mortality of prostate cancer (PCa). Olive oil is an important source of phenolic ... -
Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates
(Elsevier, 2012)Kisspeptins, the peptide products of the Kiss1 gene, were initially identified in mammals as ligands of the G protein‐coupled receptor 54 (GPR54; also termed Kiss1R) with ability to suppress tumor metastasis. In late 2003, ... -
Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched fat-1 Mice
(Public Libray of Science (PLOS), 2010)The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive ... -
Consanguinidad en el toro de lidia
(Universidad de Córdoba, Servicio de Publicaciones, 1985)Five herds of fighting caatle were examined about the inbreeding. Inbreeding coefficients from pedigrees traced-back as far as seven ancestral generations were calculated. Also was ,obtained the variation coefficient and ...