Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 194-213 de 280
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Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-kB Pathways
(MDPI, 2017)Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase reporter gene. Inhibition of HIV ... -
Neuroprotective Effects of Betulinic Acid Hydroxamate in Intraventricular Hemorrhage-Induced Brain Damage in Immature Rats
(MDPI, 2022)Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. We aimed to study in an IVH model in immature rats the neuroprotective effect of ... -
Non psychotropic cannabinoids for the treatment of inflammatory diseases
(Universidad de Córdoba, UCOPress, 2020)Medicinal cannabis and purified cannabinoids have garnered worldwide attention since millions of patients can benefit from their medical properties. Over the past few years, the endocannabinoid system (ECS) has emerged as ... -
Non-Coding RNAs in Kidney Diseases: The Long and Short of Them
(MDPI, 2021)Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a miscellaneous group of largely unknown RNA transcripts, which contain the ... -
Novel diagnostic biomarkers and therapeutic options for neuroendocrine tumors
(Universidad de Córdoba, UCOPress, 2019)Neuroendocriene tumoren (NET) vormen een heterogene groep van zeldzaam voorkomende, langzaam groeiende tumoren. NET ontstaan vanuit enterochromaffine cellen. De jaarlijkse incidentie van NET is progressief toegenomen in ... -
Novel molecular insights on the role of splicing dysregulation in cancer
(Universidad de Córdoba, UCOPress, 2022)Cancer and tumoral diseases represent one of most serious and complicated public health problems, being one of the leading causes of death in the world. The remarkable variety across cancer types, and the heterogeneity ... -
Novel regulatory mechanisms of Kiss1 neurons during reproductive axis development and in conditions of metabolic stress: Analysis of the roles of microRNAs and elements of the secretory pathway
(Universidad de Córdoba, UCOPress, 2023)Reproduction is indispensable for the perpetuation of the species. Therefore, it is safeguarded by a sophisticated network of regulatory mechanisms that ultimately controls the reproductive function by modulating the ... -
Novel regulatory pathways in the central control of puberty: analysis of the role of ceramide signaling and Mkrn3/miR-30b system
(Universidad de Córdoba, UCOPress, 2019) -
Nuevos mecanismos de control de la proteína supresora de tumores FBXW7 mediados por la quinasa DYRK2
(Universidad de Córdoba, UCOPress, 2023)The systems responsible for protein homeostasis play a fundamental role in the development of tumors. These systems recognize and degrade incomplete, misfolded proteins or act as control mechanisms for cellular processes. ... -
Nuevos triterpenos hidroxamatos como activadores de HIF. Implicaciones terapéuticas
(Universidad de Córdoba, UCOPress, 2021)El factor inducible por hipoxia (HIF) se estabiliza durante los procesos inflamatorios asociados a un gran número de patologías, produciendo cambios en la expresión génica con un profundo impacto en el microambiente tisular, ... -
Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue
(Society for Endocrinology, 2013)There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ... -
Objective Assessment of Equine Locomotor Symmetry Using an Inertial Sensor System and Artificial Intelligence: A Comparative Study
(MDPI, 2024)In horses, quantitative assessment of gait parameters, as with the use of inertial measurement units (IMUs) systems, might help in the decision-making process. However, it requires financial investment, is time-consuming, ... -
Odd- and Branched-Chain Fatty Acids in Lamb Meat as Potential Indicators of Fattening Diet Characteristics
(MDPI, 2021)There is a growing interest of researchers in meat authentication in terms of geographical and dietary background of animals, and several analytical methods have been proposed for the purpose of investigating this. We ... -
Olive Oil and the Hallmarks of Aging
(MDPI, 2016)Aging is a multifactorial and tissue-specific process involving diverse alterations regardedas the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ... -
Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer
(MDPI, 2019)Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the ... -
Ovarian stimulation with FSH reduces phosphorylation of gonadotrope progesterone receptor and LH secretion in the rat
(Society for Reproduction and Fertility, 2009)Administration of human FSH(hFSH) to cyclic rats during the dioestrous phase attenuates progesterone receptor (PR)-dependent events of the preovulatory LH surge in pro-oestrus. The increased bioactivity of the putative ... -
Papel de la Citocromo b5 reductasa-3 (CYB5R3) y del componente graso de la dieta en la fisiología y el envejecimiento del músculo esquelético
(Universidad de Córdoba, UCOPress, 2022)El envejecimiento es el declive progresivo dependiente del tiempo que viene acompañado de una disminución de la fertilidad y del aumento de la susceptibilidad del organismo a amenazas tanto endógenas como externas. A lo ... -
Papel de la NAD(P)H: quinona oxidorreductasa 1 (NQO1) en el control del crecimiento de las células animales
(Universidad de Córdoba, Servicio de Publicaciones, 2010)El control del crecimiento de las células animales depende de la percepción de señales apropiadas que permiten a las células sobrepasar diversos puntos de control, y de esta manera progresar a lo largo de las distintas ... -
Papel de la somatostanina, cortistanina y ghrelina en la desregulación celular y molecular del páncreas endocrino en situaciones metabólicas normales y extremas como la obesidad y la diabetes
(Universidad de Córdoba, Servicio de Publicaciones, 2013)El adecuado funcionamiento del eje neuroendocrino-metabólico es crucial para el mantenimiento de la homeostasis del organismo, de forma que los defectos de su regulación conducen con frecuencia a graves patologías, tales ... -
Papel del receptor endovanilloide TRPV-1 sobre la inflamación y carcinogénesis intestinal
(Universidad de Córdoba, Servicio de Publicaciones, 2011)A link between inflammation and cancer has been clearly demonstrated and underlying chronic inflammation may be of particular relevance to gastrointestinal (GI) carcinogenesis, especially in colitis-associated cancer (CAC). ...