Listar por tema "Rab18"

Mostrando ítems 1-6 de 6

    • Caracterización de Rab18 en el metabolismo lipídico de adipocitos 

      Sánchez Ceinos, Julia (Universidad de Córdoba, 2016)
      Las gotas lipídicas (LDs) son orgánulos intracelulares que coordinan el almacenamiento y la movilización de los lípidos, siendo ambos procesos especialmente importantes en las células especializadas en la gestión de estos ...

    • Iniciación de la caracterización de Interactoma de la GTPasa Rab 18 

      Peralta Matarredona, Beatriz (Universidad de Córdoba, 2015)
      Estudios previos han establecido que las Rab GTPasas funcionan como proteínas que aseguran la eficiencia y especificidad de la selección del cargo, la dirección del movimiento de las vesículas y su fusión con las membranas ...

    • Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue 

      Pulido, Marina R.; Rabanal Ruiz, Yoana; Almabouada, Farid; Díaz-Ruiz, Alberto; Burrel, María A; Vázquez, María J.; Castaño, Justo P.; Kineman, Rhonda D.; Luque, Raúl M.; Diéguez, Carlos; Vázquez-Martínez, Rafael; Malagón, María M. (Society for Endocrinology, 2013)
      There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...

    • Rab18 drift in lipid droplet and endoplasmic reticulum interactions of adipocytes under obesogenic conditions 

      López-Alcalá, J.; Soler-Vázquez, M. Carmen; Tercero-Alcázar, C.; Sánchez Ceinos, Julia; Guzmán Ruiz, R.; Malagón, María M.; Gordon, Ana (MDPI, 2023)
      The adipose tissue stores excess energy in the form of neutral lipids within adipocyte lipid droplets (LDs). The correct function of LDs requires the interaction with other organelles, such as the endoplasmic reticulum ...

    • Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity 

      Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García Navarro, S.; Gracia-Navarro, F.; Tinahones, Francisco J.; López-Miranda, José; Frühbeck, Gema; Vázquez Martínez, Rafael; Malagón, María M. (PLOS, 2011)
      Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...

    • Rab18 is reduced in pituitary tumors cusing acromegaly and its overexpression reverts growth hormone hypersecretion 

      Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Pulido, Marina R.; Jiménez Reina, L.; Quintero, Ana; Leal-Cerro, Alfonso; Soto, Alfonso; Webb, Susan M.; Sucunza, Nuria; Bartumeus, Frederic; Benito-López, Pedro; Galvez-Moreno, María A.; Castaño, Justo P.; Malagón, María M. (Oxford Academic, 2008)
      Context: Rab proteins regulate the sequential steps of intracellular membrane transport. Alterations of these GTPases and their associated proteins are emerging as the underlying cause for several human diseases involving ...