Mostrando ítems 191-195 de 617

    • Quantitative proteomics and bioinformatic analysis provide new insight into the dynamic response of porcine intestine to Salmonella Typhimurium 

      Collado-Romero, Melania; Aguilar, Carmen; Arce Jiménez, Cristina; Lucena, Concepción; Codrea, Marius C.; Morera Sanz, L.; Bendixen, Emoke; Moreno, Ángela; Garrido, Juan J. (Frontiers, 2015)
      The enteropathogen Salmonella Typhimurium (S. Typhimurium) is the most commonly non-typhoideal serotype isolated in pig worldwide. Currently, one of the main sources of human infection is by consumption of pork meat. ...
    • An AP Endonuclease Functions in Active DNA Demethylation and Gene Imprinting in Arabidopsis 

      Li, Yan; Córdoba-Cañero, Dolores; Qian, Weiqiang; Zhu, Xiaohong; Tang, Kai; Zhang, Huiming; Rodríguez Ariza, Rafael; Roldán-Arjona, Teresa; Zhu, Jian-Kang (Public Library of Science, 2015)
      Active DNA demethylation in plants occurs through base excision repair, beginning with removal of methylated cytosine by the ROS1/DME subfamily of 5-methylcytosine DNA glycosylases. Active DNA demethylation in animals ...
    • Early steps of active DNA demethylation initiated by ROS1 glycosylase require three putative helix-invading residues 

      Parrilla-Doblas, Jara; Ponferrada-Marín, María Isabel; Roldán-Arjona, Teresa; Rodríguez Ariza, Rafael (Oxford University Press, 2013)
      Active DNA demethylation is crucial for epigenetic control, but the underlying enzymatic mechanisms are incompletely understood. REPRESSOR OF SILENCING 1 (ROS1) is a 5-methylcytosine (5-meC) DNA glycosylase/lyase that ...
    • Demethylation initiated by ROS1 glycosylase involves random sliding along DNA 

      Ponferrada-Marín, María Isabel; Roldán-Arjona, Teresa; Rodríguez Ariza, Rafael (Oxford University Press, 2012)
      Active DNA demethylation processes play a critical role in shaping methylation patterns, yet our understanding of the mechanisms involved is still fragmented and incomplete. REPRESSOR OF SILENCING 1 (ROS1) is a prototype ...
    • How alkalinization drives fungal pathogenicity 

      Ribeiro Fernandes, Tânia Alícia; Segorbe, David; Prusky, Dov; Di Pietro, Antonio (Public Library of Science, 2017)
      pH governs most, if not all, processes of life. In fungi, ambient pH acts as a potent regulator of growth and development [1]. Studies conducted primarily in the 2 model organisms Saccharomyces cerevisiae and Aspergillus ...