Listar DMed-Artículos, capítulos... por autor "75d44eea-2cf1-47aa-9e88-1f44ac2c34f3"
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Basal VEGF-A and ACE Plasma Levels of Metastatic Colorectal-Cancer Patients Have Prognostic Value for First-Line Treatment with Chemotherapy Plus Bevacizumab
Ortiz-Morales, M. José; Toledano-Fonseca, Marta; Mena-Osuna, Rafael; Cano, M. Teresa; Gómez-España, M. Auxiliadora; Haba-Rodríguez, Juan R. de la; Rodríguez-Ariza, Antonio; Aranda Aguilar, Enrique (MDPI, 2022)The identification of factors that respond to anti-angiogenic therapy would represent a significant advance in the therapeutic management of metastatic-colorectal-cancer (mCRC) patients. We previously reported the relevance ... -
Circulating Cell-Free DNA-Based Liquid Biopsy Markers for the Non-Invasive Prognosis and Monitoring of Metastatic Pancreatic Cancer
Toledano-Fonseca, Marta; Cano, M. Teresa; Inga, Elizabeth; Rodríguez-Alonso, Rosa; Gómez-España, M. Auxiliadora; Guil-Luna, Silvia; Mena-Osuna, Rafael; Haba-Rodríguez, Juan R. de la; Rodríguez-Ariza, Antonio; Aranda Aguilar, Enrique (MDPI, 2020)Liquid biopsy may assist in the management of cancer patients, which can be particularly applicable in pancreatic ductal adenocarcinoma (PDAC). In this study, we investigated the utility of circulating cell-free DNA ... -
Clinical Utility of microRNAs in Exhaled Breath Condensate as Biomarkers for Lung Cancer
Pérez Sánchez, Carlos; Barbarroja, Nuria; Pantaleão, Lucas C.; López-Sánchez, Laura M.; Ozanne, Susan E.; Jurado-Gámez, Bernabé; Jurado-Gámez, Bernabé; Aranda Aguilar, Enrique; López-Pedrera, Ch.; Rodríguez-Ariza, Antonio (MDPI, 2021)This study represents a novel proof of concept of the clinical utility of miRNAs from exhaled breath condensate (EBC) as biomarkers of lung cancer (LC). Genome-wide miRNA profiling and machine learning analysis were performed ... -
Metabolic shift underlies tumor progression and immune evasion in S-nitrosoglutathione reductase-deficient cancer
Mena-Osuna, Rafael; Mantrana, Ana; Guil-Luna, Silvia; Sánchez, María-Teresa; Navarrete, Carmen; Morales-Ruiz, T.; Rivas-Crespo, Aurora; Toledano-Fonseca, Marta; García-Ortíz, María Victoria; García Jurado, Gema; Gómez-España, M. Auxiliadora; González Fernández, Rafael A.; Villar, Carlos; Medina Fernández, Francisco Javier; Villalba, José Manuel; Aranda Aguilar, Enrique; Rodríguez-Ariza, Antonio (Wiley, 2023)S-nitrosoglutathione reductase (GSNOR) is a denitrosylase enzyme that has been suggested to play a tumor suppressor role, although the mechanisms responsible are still largely unclear. In this study, we show that GSNOR ... -
Nuclear Translocation of b-Catenin during Mesenchymal Stem Cells Differentiation into Hepatocytes Is Associated with a Tumoral Phenotype
Herencia, Carmen; Martínez-Moreno, Julio M.; Herrera, Concepción; Corrales, Fernando J.; Santiago-Mora, Raquel; Espejo, Isabel; Barcos, Montserrat; Almadén Peña, Yolanda; Mata, Manuel de la; Rodríguez-Ariza, Antonio; Muñoz-Castañeda, Juan R. (Public Libray of Science (PLOS), 2012)Wnt/b-catenin pathway controls biochemical processes related to cell differentiation. In committed cells the alteration of this pathway has been associated with tumors as hepatocellular carcinoma or hepatoblastoma. The ... -
The Combination of Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio with Liquid Biopsy Biomarkers Improves Prognosis Prediction in Metastatic Pancreatic Cancer
Toledano-Fonseca, Marta; Cano, M. Teresa; Inga, Elizabeth; Gómez-España, M. Auxiliadora; Guil-Luna, Silvia; García-Ortiz, M.V.; Mena-Osuna, Rafael; Haba-Rodríguez, Juan R. de la; Rodríguez-Ariza, Antonio; Aranda Aguilar, Enrique (MDPI, 2021)Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a highly inflammatory microenvironment and liquid biopsy has emerged as a promising tool for the noninvasive analysis of this tumor. In this study, plasma ...