Listar DMed-Artículos, capítulos... por autor "77438ad0-8c13-4838-98d1-2dfa5459b79d"
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A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study
Villasanta-González, Alejandro; Alcalá Díaz, Juan Francisco; Vals-Delgado, Cristina; Arenas, Antonio Pablo; Cardelo, Magdalena P.; Romero-Cabrera, Juan Luis; Rodríguez-Cantalejo, Fernando; Delgado-Lista, Javier; Malagón, María M.; Pérez-Martínez, Pablo; Schulze, Matthias B.; Camargo García, A.; López-Miranda, José (Springer, 2021)Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ... -
A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet
Pérez-Martínez, Pablo; Pérez-Jiménez, Francisco; Bellido, Cecilia; Ordovas, José M.; Moreno, Juan Antonio; Marín, Carmen; Gómez, Purificación; Delgado-Lista, Javier; Fuentes, Francisco; López Miranda, José (Oxford Academic, 2005)Scavenger receptor class B type I (SCARB1) was described as the first high-density lipoprotein receptor. Increasing evidence indicates that SCARB1 plays additional roles particularly in type 2 diabetes mellitus. Our aim ... -
A single nucleotide polymorphism of the apolipoprotein A-V gene -1131T>C modulates postprandial lipoprotein metabolism
Moreno, Rafael; Pérez-Jiménez, Francisco; Marín, Carmen; Moreno, Juan Antonio; Gómez, Purificación; Bellido, Cecilia; Pérez Martínez, Pablo; Jiménez Gómez, Yolanda; José Fuentes, Francisco; López Miranda, José (Elsevier, 2006)The Apolipoprotein A–V (apoA–V) gene promoter polymorphism −1131T > C modulates triacylglycerol (TG) concentrations. We evaluate whether this polymorphism could be involved in the interindividual variability observed during ... -
Aceite de oliva y prevención cardiovascular: más que una grasa
Delgado Lista, José; López Segura, Fernando; Pérez-Martínez, Pablo; Pérez-Jiménez, Francisco; López-Miranda, José (Instituto de Estudio Jiennenses, 2007) -
Apolipoprotein E gene promoter -219G->T polymorphism increases LDL-cholesterol concentrations and susceptibility to oxidation in response to a diet rich in saturated fat.
Moreno, Juan Antonio; Pérez-Jiménez, Francisco; Marín, Carmen; Gómez, Purificación; Pérez-Martínez, Pablo; Moreno, Rafael; Bellido, Cecilia; Fuentes, Francisco; López Miranda, José (Elsevier, 2004)Background The apolipoprotein E (APOE) gene promoter polymorphism (−219G→T) has been associated with increased risk of myocardial infarction, premature coronary artery disease, and decreased plasma apolipoprotein E ... -
Association between Diet Quality and Risk of Type 2 Diabetes Mellitus in Patients with Coronary Heart Disease: Findings from the CORDIOPREV Study
Rivas García, Lorenzo; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Rangel-Zuñiga, Oriol Alberto; López-Moreno, Alejandro; Malagón, María M.; Katsiki, Niki; Pérez Martínez, Pablo; López Miranda, José; Delgado-Lista, Javier (MDPI, 2024)The incidence of type 2 diabetes mellitus (T2DM) is growing in Western countries. Nutritional interventions that promote high-quality dietary patterns could help reverse this trend. We aimed to evaluate whether changes in ... -
Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial
Roncero-Ramos, Irene; Gutiérrez Mariscal, Francisco Miguel; Gómez Delgado, Francisco; Villasanta-González, Alejandro; Torres‑Peña, J.D.; Cruz‐Ares, Silvia de la; Rangel Zúñiga, Oriol Alberto; Luque, Raúl M.; Ordovas, José M.; Delgado-Lista, Javier; Pérez-Martínez, Pablo; Camargo García, A.; Alcalá Díaz, Juan Francisco; López-Miranda, José (Elsevier, 2021)In order to assess whether previous hepatic IR (Hepatic-IR fasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose- lowering treatment, newly-diagnosed type 2 diabetes ... -
Diabetes Remission Is Modulated by Branched Chain Amino Acids According to the Diet Consumed: From the CORDIOPREV Study
Cardelo, Magdalena P.; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; López Moreno, Javier; Villasanta-González, Alejandro; Arenas de Larriva, Antonio P.; Cruz Ares, Silvia de la; Delgado-Lista, Javier; Rodríguez-Cantalejo, Fernando; Luque, Raúl M.; Ordovás, José María; Pérez Martínez, Pablo; Camargo García, A.; López Miranda, José (Wiley, 2021)Scope: Branched Chain Amino Acids (BCAA) plasma levels may be differentially associated with type 2 diabetes mellitus (T2DM) remission through the consumption of the Mediterranean diet (Med) and a low-fat (LF) diet. Methods: ... -
Diet and SIRT1 Genotype Interact to Modulate Aging-Related Processes in Patients with Coronary Heart Disease: From the CORDIOPREV Study
Hidalgo-Moyano, Cristina; Rangel-Zuñiga, Oriol Alberto; Gómez Delgado, Francisco; Alcalá Díaz, Juan Francisco; Rodríguez-Cantalejo, Fernando; Yubero-Serrano, Elena M.; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Camargo García, A.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2022)We investigated whether long-term consumption of two healthy diets (low-fat (LF) or Mediterranean (Med)) interacts with SIRT1 genotypes to modulate aging-related processes such as leucocyte telomere length (LTL), oxidative ... -
Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations
Pérez-Caballero, Ana I.; García-Ríos, Antonio; Gómez-Luna, María J.; Gómez-Luna, Purificación; Dembinska-Kiec, Aldona; Rodríguez-Cantalejo, Fernando; Camargo García, A.; Marín, Carmen; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; Tinahones, Francisco J.; Pérez-Jiménez, Francisco; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2012)Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked to higher cardiovascular risk. To date, there is little information about the additional impact of ... -
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study
Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ... -
Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study
Martín-Piedra, Laura; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Romero-Cabrera, Juan Luis; Torres‑Peña, J.D.; Caballero-Villarraso, Javier; Luque, Raúl M.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2021)Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing ... -
Glucokinase Regulatory Protein Genetic Variant Interacts with Omega-3 PUFA to Influence Insulin Resistance and Inflammation in Metabolic Syndrome
García-Ríos, Antonio; Mc Monagle, Jolene; Gulseth, Hanne L.; Ordovás, José María; Shaw, Danielle I.; Karlström, Brita; Kiec-Wilk, Beata; Blaak, Ellen E.; Helal, Olfa; Malczewska-Malec, Malgorzata; Defoort, Catherine; Risérus, Ulf; Saris, Wim H.M.; Lovegrove, Julie A.; Drevon, Christian A.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2011)Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism. Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose ... -
Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study
León Acuña, Ana; Delgado Lista, José; Torres‑Peña, J.D.; López Moreno, Javier; García-Ríos, Antonio; Marín, Carmen; Gómez Delgado, Francisco; Caballero, J.; Van‑Ommen, B.; Malagón, María M.; Pérez-Martínez, Pablo; Alcalá Díaz, Juan Francisco; Camargo García, A.; López-Miranda, José (BioMed Central, 2016)Background/aims: Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, ... -
Hypertriglyceridemia Influences the Degree of Postprandial Lipemic Response in Patients with Metabolic Syndrome and Coronary Artery Disease: From the Cordioprev Study
Alcalá Díaz, Juan Francisco; Delgado-Lista, Javier; Pérez-Martínez, Pablo; Quintana-Navarro, Gracia M.; Gómez-Luna, Purificación; Camargo García, A.; Almadén Peña, Yolanda; Caballero, Javier; Marín, Carmen; García-Ríos, Antonio; Tinahones, Francisco J.; Ordovas, José M.; Pérez-Jímenez, Francisco; López-Miranda, José (PLOS, 2014)Objective To determine whether metabolic syndrome traits influence the postprandial lipemia response of coronary patients, and whether this influence depends on the number of MetS criteria. Materials and Methods 1002 ... -
Impact of the Content of Fatty Acids of Oral Fat Tolerance Tests on Postprandial Triglyceridemia: Systematic Review and Meta-Analysis
Monfort-Pires, Milena; Delgado-Lista, Javier; Gómez Delgado, Francisco; López-Miranda, José; Pérez-Martínez, Pablo; Gouvea Ferreira, Sandra Roberta (MDPI, 2016)Whether the content of saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA) could differently influence postprandial triglycerides (TG) is unknown. We examined possible differences in the ... -
In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation
Martínez-Moreno, Julio M.; Muñoz-Castañeda, Juan R.; Herencia, Carmen; Montes de Oca, Addy; Estepa Nieto, José Carlos; Canalejo, Rocío; Rodríguez-Ortiz, Maria E.; Aguilera Tejero, Escolástico; Canalejo, Antonio; Rodríguez, Mariano; Almadén Peña, Yolanda; Pérez-Martínez, Pablo (American Journal of Physiology, 2012)The present study investigates the differential effect of two vitamin D receptor agonists, calcitriol and paricalcitol, on human aortic smooth muscle cells calcification in vitro. Human vascular smooth muscle cells were ... -
Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
Talavera-García, Eva; Delgado-Lista, Javier; García-Ríos, Antonio; Delgado-Casado, Nieves; Gómez-Luna, Purificación; Gómez-Garduño, Ángela; Gómez Delgado, Francisco; Alcalá Díaz, Juan Francisco; Yubero-Serrano, Elena M.; Marín, Carmen; Pérez-Caballero, Ana I.; Fuentes-Jiménez, Francisco J.; Rodríguez-Cantalejo, Fernando; Tinahones, Francisco J.; Ordovás, José María; Pérez-Jiménez, Francisco; Pérez-Martínez, Pablo; López-Miranda, José; Camargo García, A. (Public Library of Science, 2016)Background Recent data suggest that the presence of associated metabolic abnormalities may be important modifiers of the association of obesity with a poorer prognosis in coronary heart disease. We determined the influence ... -
Long-term effect of a dietary intervention with two-healthy dietary approaches on food intake and nutrient density in coronary patients: results from the CORDIOPREV trial
Cano‑Ibáñez, Naomi; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; Rangel Zúñiga, Oriol Alberto; Camargo García, A.; Yubero-Serrano, Elena M.; Pérez‑Corral, Isabel; Arenas de Larriva, Antonio P.; García-Ríos, Antonio; Pérez-Martínez, Pablo; Delgado-Lista, Javier; López-Miranda, José (Springer, 2022)Background: Cardiovascular disease (CVD) is the leading cause of disease burden in the world by non-communicable diseases. Nutritional interventions promoting high-quality dietary patterns with low caloric intake value and ... -
Owning a Pet Is Associated with Changes in the Composition of Gut Microbiota and Could Influence the Risk of Metabolic Disorders in Humans
Arenas-Montes, Javier; Pérez-Martínez, Pablo; Vals-Delgado, Cristina; Romero-Cabrera, Juan Luis; Cardelo, Magdalena P.; León Acuña, Ana; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; López-Miranda, José; Camargo García, A.; Pérez-Jiménez, Francisco (MDPI, 2021)Pet ownership positively influences clinical outcomes in cardiovascular prevention. Additionally, cardiovascular disease (CVD) has been previously linked to microbiota dysbiosis. We evaluated the influence of owning a pet ...