Listar DMed-Artículos, capítulos... por autor "d64f393a-f5a6-481c-b871-3aadb6bd2255"
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A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet
Pérez-Martínez, Pablo; Pérez-Jiménez, Francisco; Bellido, Cecilia; Ordovas, José M.; Moreno, Juan Antonio; Marín, Carmen; Gómez, Purificación; Delgado-Lista, Javier; Fuentes, Francisco; López Miranda, José (Oxford Academic, 2005)Scavenger receptor class B type I (SCARB1) was described as the first high-density lipoprotein receptor. Increasing evidence indicates that SCARB1 plays additional roles particularly in type 2 diabetes mellitus. Our aim ... -
A single nucleotide polymorphism of the apolipoprotein A-V gene -1131T>C modulates postprandial lipoprotein metabolism
Moreno, Rafael; Pérez-Jiménez, Francisco; Marín, Carmen; Moreno, Juan Antonio; Gómez, Purificación; Bellido, Cecilia; Pérez Martínez, Pablo; Jiménez Gómez, Yolanda; José Fuentes, Francisco; López Miranda, José (Elsevier, 2006)The Apolipoprotein A–V (apoA–V) gene promoter polymorphism −1131T > C modulates triacylglycerol (TG) concentrations. We evaluate whether this polymorphism could be involved in the interindividual variability observed during ... -
Apolipoprotein E gene promoter -219G->T polymorphism increases LDL-cholesterol concentrations and susceptibility to oxidation in response to a diet rich in saturated fat.
Moreno, Juan Antonio; Pérez-Jiménez, Francisco; Marín, Carmen; Gómez, Purificación; Pérez-Martínez, Pablo; Moreno, Rafael; Bellido, Cecilia; Fuentes, Francisco; López Miranda, José (Elsevier, 2004)Background The apolipoprotein E (APOE) gene promoter polymorphism (−219G→T) has been associated with increased risk of myocardial infarction, premature coronary artery disease, and decreased plasma apolipoprotein E ... -
Phenolic Content of Virgin Olive Oil Improves Ischemic Reactive Hyperemia in Hypercholesterolemic Patients
Ruano, Juan; López Miranda, José; Fuentes, Francisco; Moreno, Juan Antonio; Bellido, Cecilia; Pérez-Martínez, Pablo; Lozano, Aquiles; Gómez, Purificación; Jiménez, Yolanda; Pérez-Jiménez, Francisco (Elsevier, 2005)The goal of this study was to evaluate the effects of the phenolic content of virgin olive oil on endothelial reactivity. Background Endothelial-dependent vasodilatation is impaired during the postprandial state, and ... -
The APOB -516C/T polymorphism has no effect on lipid and apolipoprotein response following changes in dietary fat intake in a healthy population
Pérez Martínez, Pablo; Pérez Jiménez, Francisco; Ordovás, José María; Bellido, Cecilia; Moreno, Juan; Gómez, Purificación; Marín, Carmen; Fernández de la Puebla, Rafael Ángel; Paniagua, Juan Antonio; López Miranda, José (Elsevier, 2007)Our goal was to determine whether the presence of the −516C/T polymorphism in the APOB gene promoter modifies the lipid response to changes in the amount and quality of dietary fat. We studied 97 young healthy volunteers ... -
The Effect of Dietary Fat on LDL Size Is Influenced by Apolipoprotein E Genotype in Healthy Subjects
Moreno, Juan Antonio; Pérez-Jiménez, Francisco; Marín, Carmen; Gómez, Purificación; Pérez-Martínez, Pablo; Moreno, Rafael; Bellido, Cecilia; Fuentes, Francisco; López Miranda, José (American Society for Nutrition, 2004)LDL particle size is dependent on both genetic factors and environmental factors such as dietary fat composition. The apolipoprotein E (apoE) genotype is a major genetic determinant of LDL size. Thus, the aim of this work ...