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Dietary Mg Supplementation Decreases Oxidative Stress, Inflammation, and Vascular Dysfunction in an Experimental Model of Metabolic Syndrome with Renal Failure
López-Baltanás, Rodrigo; Rodríguez-Ortiz, Maria E.; Díaz Tocados, Juan Manuel; Martínez-Moreno, Julio M.; Membrives, Cristina; Rodelo Haad, Cristian Roberto; Pendón-Ruiz de Mier, María V.; Pendón-Ruiz de Mier, María V.; Rodríguez, Mariano; Canalejo, Antonio; Almadén Peña, Yolanda; Muñoz-Castañeda, Juan R. (MDPI, 2023)whether a dietary Mg supplementation might attenuate vascular dysfunction through the modulation of oxidative stress and inflammation in concurrent MetS and CKD. Methods: A rat model of MetS (Zucker strain) with CKD (5/6 ... -
Klotho/FGF23 and Wnt Signaling as Important Players in the Comorbidities Associated with Chronic Kidney Disease
Muñoz-Castañeda, Juan R.; Rodelo Haad, Cristian Roberto; Pendón-Ruiz de Mier, María V.; Martín-Malo, Alejandro; Santamaría, Rafael; Rodríguez, Mariano (MDPI, 2020)Fibroblast Growth Factor 23 (FGF23) and Klotho play an essential role in the regulation of mineral metabolism, and both are altered as a consequence of renal failure. FGF23 increases to augment phosphaturia, which prevents ...