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Mostrando ítems 44-63 de 105

    • Enumeration and Characterization of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization 

      Espejo-Cruz, María Lola; González Rubio, Sandra; Espejo, Juan J.; Zamora-Olaya, Javier; Alejandre, Rafael; Prieto-Torre, María; Linares Luna, Clara Isabel; Guerrero-Misas, Marta; Barrera-Baena, Pilar; Poyato-González, Antonio; Sánchez-Frías, Marina; Ayllón Terán, M. Dolores; Rodríguez-Perálvarez, Manuel; Mata, Manuel de la; Ferrín, Gustavo (MDPI, 2023)
      Circulating tumor cells (CTCs), and particularly circulating cancer stem cells (cCSC), are prognostic biomarkers for different malignancies and may be detected using liquid biopsies. The ex vivo culture of cCSCs would ...

    • Epidemiologic Behavior of Obesity in the Maracaibo City Metabolic Syndrome Prevalence Study 

      López-Miranda, José; Bermúdez Pirela, Valmore José; Pacheco, Maikol; Rojas, Joselyn; Córdova, Evelyn; Velázquez, Rossibel; Carrillo, Daniela; Parra, María G.; Toledo, Alexandra; Añez, Roberto; Fonseca, Eneida; París Marcano, Rafael; Cano, Clímaco; López-Miranda, José (Public Libray of Science (PLOS), 2012)
      Introduction: Obesity is a worldwide public health issue. Since the epidemiological behaviour of this disease is not well established in our country, the purpose of this study was to determinate its prevalence in the ...

    • Ethnicity and Clinical Outcomes in Patients Hospitalized for COVID-19 in Spain: Results from the Multicenter SEMI-COVID-19 Registry 

      Ramos-Rincón, José Manuel; Cobos-Palacios, Lidia; López-Sampalo, Almudena; Ricci, Michele; Rubio-Rivas, Manuel; Martos-Pérez, Francisco; Lalueza-Blanco, Antonio; Moragón-Ledesma, Sergio; Fonseca-Aizpuru, Eva-María; García-García, Gema-María; Beato-Pérez, José-Luis; Josa-Laorden, Claudia; Arnalich-Fernández, Francisco; Molinos-Castro, Sonia; Torres‑Peña, J.D.; Artero, Arturo; Vargas-Núñez, Juan-Antonio; Méndez-Bailón, Manuel; Loureiro-Amigo, Jose; Hernández-Garrido, María-Soledad; Peris-García, Jorge; López-Reboiro, Manuel-Lorenzo; Barón-Franco, Bosco; Casas-Rojo, José Manuel; Gómez-Huelgas, Ricardo; SEMI‐COVID‐19 Network (MDPI, 2022)
      This work aims to analyze clinical outcomes according to ethnic groups in patients hospitalized for COVID-19 in Spain. (2) Methods: This nationwide, retrospective, multicenter, observational study analyzed hospitalized ...

    • Evaluation of the Effect of Limosilactobacillus fermentum CECT5716 on Gastrointestinal Infections in Infants: A Systematic Review and Meta-Analysis 

      Pastor-Villaescusa, Belén; Blanco-Rojo, Ruth; Olivares, Mónica (MDPI, 2021)
      Reducing the incidence of gastrointestinal infections (GIs) that occur at early stages to mitigate hospitalizations and treatments with adverse effects is a promising strategy for providing well-being to infants and their ...

    • Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study 

      Martín-Piedra, Laura; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Romero-Cabrera, Juan Luis; Torres‑Peña, J.D.; Caballero-Villarraso, Javier; Luque, Raúl M.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2021)
      Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing ...

    • Expression of DDX11 and DNM1L at the 12p11 Locus Modulates Systemic Lupus Erythematosus Susceptibility 

      Saeed, Mohammad; Ibáñez-Costa, Alejandro; Patiño-Trives, Alejandra Mª; Muñoz-Barrera, Laura; Collantes Estévez, Eduardo; Aguirre, María Ángeles; López-Pedrera, Ch. (MDPI, 2021)
      This study employed genetic and functional analyses using OASIS meta-analysis of multiple existing GWAS and gene-expression datasets to identify novel SLE genes. Methods: Four hundred and ten genes were mapped using SNIPPER ...

    • Genetic landscape of Segawa disease in Spain. Long-term treatment outcomes 

      Fernández Ramos, Joaquín Alejandro; Torre‑Aguilar, M. J. de la; Quintáns, Beatriz; Pérez Navero, Juan Luis; Beyer, Katrin; López-Laso, Eduardo (Elsevier, 2021)
      Introduction In 2009, we described a possible founder effect of autosomal dominant Segawa disease in Córdoba (Spain) due to mutation c.265C>T (p. Q89*) in the GCH1 gene. We present a retrospective multicentre study aimed ...

    • Glucokinase Regulatory Protein Genetic Variant Interacts with Omega-3 PUFA to Influence Insulin Resistance and Inflammation in Metabolic Syndrome 

      García-Ríos, Antonio; Mc Monagle, Jolene; Gulseth, Hanne L.; Ordovás, José María; Shaw, Danielle I.; Karlström, Brita; Kiec-Wilk, Beata; Blaak, Ellen E.; Helal, Olfa; Malczewska-Malec, Malgorzata; Defoort, Catherine; Risérus, Ulf; Saris, Wim H.M.; Lovegrove, Julie A.; Drevon, Christian A.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2011)
      Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism. Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose ...

    • Helicobacter Species and Hepato-Biliary Tract Malignancies: A Systematic Review and Meta-Analysis 

      Gros, Beatriz; Gómez Pérez, Alberto; Pleguezuelo, María; Serrano Ruiz, Francisco Javier; Serrano Ruiz, Francisco Javier; de la Mata, Manuel; Rodríguez-Perálvarez, Manuel (MDPI, 2023)
      Helicobacter species may cause chronic inflammation of the biliary tract, but its relationship with cancer is controversial. We performed a systematic review and meta-analysis to evaluate the association between Helicobacter ...

    • Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study 

      León Acuña, Ana; Delgado Lista, José; Torres‑Peña, J.D.; López Moreno, Javier; García-Ríos, Antonio; Marín, Carmen; Gómez Delgado, Francisco; Caballero, J.; Van‑Ommen, B.; Malagón, María M.; Pérez-Martínez, Pablo; Alcalá Díaz, Juan Francisco; Camargo García, A.; López-Miranda, José (BioMed Central, 2016)
      Background/aims: Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, ...

    • Hypertriglyceridemia Influences the Degree of Postprandial Lipemic Response in Patients with Metabolic Syndrome and Coronary Artery Disease: From the Cordioprev Study 

      Alcalá Díaz, Juan Francisco; Delgado-Lista, Javier; Pérez-Martínez, Pablo; Quintana-Navarro, Gracia M.; Gómez-Luna, Purificación; Camargo García, A.; Almadén Peña, Yolanda; Caballero, Javier; Marín, Carmen; García-Ríos, Antonio; Tinahones, Francisco J.; Ordovas, José M.; Pérez-Jímenez, Francisco; López-Miranda, José (PLOS, 2014)
      Objective To determine whether metabolic syndrome traits influence the postprandial lipemia response of coronary patients, and whether this influence depends on the number of MetS criteria. Materials and Methods 1002 ...

    • Identification of myosin light chain protein as a major fish allergen 

      Espinazo Romeu, Marisa; Letrán Camacho, Antonio; Moreno Aguilar, Carmen; Jurado Roger, Aurora; Moreno Benítez, Francisco (Wiley, 2022)
      The prevalence of food allergy has been increasing worldwide in the last 10 years. Currently, 2%–8% of the population in Western countries suffers from some type of food allergy. In Spain, seafood allergy has increased ...

    • Impact of the Content of Fatty Acids of Oral Fat Tolerance Tests on Postprandial Triglyceridemia: Systematic Review and Meta-Analysis 

      Monfort-Pires, Milena; Delgado-Lista, Javier; Gómez Delgado, Francisco; López-Miranda, José; Pérez-Martínez, Pablo; Gouvea Ferreira, Sandra Roberta (MDPI, 2016)
      Whether the content of saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA) could differently influence postprandial triglycerides (TG) is unknown. We examined possible differences in the ...

    • Importancia del momento en que se realiza la ingestión de los nutrientes 

      Pérez-Guisado, Joaquín (Comunidad Virtual Ciencias del Deporte y Universidad Autónoma de Madrid, 2009)
      En el progreso del deportista, saber cual es el momento oportuno a la hora de ingerir los nutrientes, y la proporción de dichos nutrientes, puede marcar una mejor asimilación y utilización de los mismos. Además de la ...

    • In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation 

      Martínez-Moreno, Julio M.; Muñoz-Castañeda, Juan R.; Herencia, Carmen; Montes de Oca, Addy; Estepa Nieto, José Carlos; Canalejo, Rocío; Rodríguez-Ortiz, Maria E.; Aguilera Tejero, Escolástico; Canalejo, Antonio; Rodríguez, Mariano; Almadén Peña, Yolanda; Pérez-Martínez, Pablo (American Journal of Physiology, 2012)
      The present study investigates the differential effect of two vitamin D receptor agonists, calcitriol and paricalcitol, on human aortic smooth muscle cells calcification in vitro. Human vascular smooth muscle cells were ...

    • Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study) 

      Talavera-García, Eva; Delgado-Lista, Javier; García-Ríos, Antonio; Delgado-Casado, Nieves; Gómez-Luna, Purificación; Gómez-Garduño, Ángela; Gómez Delgado, Francisco; Alcalá Díaz, Juan Francisco; Yubero-Serrano, Elena M.; Marín, Carmen; Pérez-Caballero, Ana I.; Fuentes-Jiménez, Francisco J.; Rodríguez-Cantalejo, Fernando; Tinahones, Francisco J.; Ordovás, José María; Pérez-Jiménez, Francisco; Pérez-Martínez, Pablo; López-Miranda, José; Camargo García, A. (Public Library of Science, 2016)
      Background Recent data suggest that the presence of associated metabolic abnormalities may be important modifiers of the association of obesity with a poorer prognosis in coronary heart disease. We determined the influence ...

    • Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance 

      Navarro-Ruiz, Carmen; Soler-Vázquez, M. Carmen; Díaz-Ruiz, Alberto; Peinado, Juan R.; Nieto Calonge, Andrea; Sánchez Ceinos, Julia; Tercero-Alcázar, C.; López-Alcalá, J.; Rangel Zúñiga, Oriol Alberto; Membrives, Antonio; López-Miranda, José; Malagón, María M.; Gúzman-Ruiz, Rocío (MDPI, 2022)
      Background: Obesity is characterized by adipose tissue dysregulation and predisposes individuals to insulin resistance and type 2 diabetes. At the molecular level, adipocyte dysfunction has been linked to obesity-triggered ...

    • Influencia de la fuerza muscular isométrica de las extremidades superiores en el estrés oxidativo en niños 

      Benítez Sillero, Juan de Dios; Pérez Navero, Juan Luis; Gil Campos, Mercedes; Guillén del Castillo, Manuel; Tasset, Inmaculada; Túnez, Isaac (Ramón Cantó Alcaraz, 2011)
      El ejercicio físico puede producir estrés oxidativo en el individuo lo que pueden condicionar el riesgo cardiovascular en niños y adolescentes. Este estudio pretende analizar el estrés oxidativo según la fuerza muscular ...

    • Informe sobre el aborto 

      Ruiz Ortiz, Julio; Martín Lozano, José Manuel; Barasona Villarejo, María José; Ruiz Ortiz, Martín; Sevilla Bujalance, Juan Luis (2012-02-07)

    • Intraoperative metabolic changes associated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy 

      Rubio‑López, Jesús David; Durán-Martínez, Manuel; Moreno-Blázquez, Andrea; Rodríguez-Ortiz, Lidia; Rufián-Andújar, Blanca; Valenzuela-Molina, Francisca; Casado Adam, Ángela; Sánchez Hidalgo, Adolfo Jorge; Rufián Peña, Sebastián; Romero-Ruiz, Antonio; Briceño Delgado, Francisco Javier; Arjona-Sánchez, Álvaro (Springer, 2023)
      Background: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) causes considerable hemodynamic, respiratory, and metabolic changes during the perioperative period. Objectives: To evaluate ...