• Glucokinase Regulatory Protein Genetic Variant Interacts with Omega-3 PUFA to Influence Insulin Resistance and Inflammation in Metabolic Syndrome 

      García-Ríos, Antonio; Mc Monagle, Jolene; Gulseth, Hanne L.; Ordovás, José María; Shaw, Danielle I.; Karlström, Brita; Kiec-Wilk, Beata; Blaak, Ellen E.; Helal, Olfa; Malczewska-Malec, Malgorzata; Defoort, Catherine; Risérus, Ulf; Saris, Wim H.M.; Lovegrove, Julie A.; Drevon, Christian A.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2011)
      Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism. Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose ...
    • Two independent apolipoprotein A5 haplotypes modulate postprandial lipoprotein metabolism in a healthy caucasian population 

      Moreno-Luna, Rafael; Pérez Jiménez, Francisco; Marín, Carmen; Pérez Martínez, Pablo; Gómez, Purificación; Jiménez Gómez, Yolanda; Delgado-Lista, Javier; Moreno, Juan; Tanaka, Toshiko; Ordovás, José María; López Miranda, José (Endocrine Society, 2007)
      Background: Apolipoprotein A5 (APOA5) plays an important role in plasma triacylglycerol (TG) homeostasis. Five polymorphisms (1131T>C, c.-3A>G, c.56C>G, IVS3+476G>A, and c.1259T>C) in the APOA5 gene define three common ...