Structural identifiability of a model for the acetic acid fermentation process
Autor
Jiménez Hornero, Jorge
Santos-Dueñas, Inés María
García García, Isidoro
Editor
ElsevierFecha
2008Materia
ModellingStructural identifiability
Parameter estimation
Acetic acid fermentation
Vinegar
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Modelling has proved an essential tool for addressing research into biotechnological processes, particularly with a view to their optimization and control. Parameter estimation via optimization approaches is among the major steps in the development of biotechnology models. In fact, one of the first tasks in the development process is to determine whether the parameters concerned can be unambiguously determined and provide meaningful physical conclusions as a result. The analysis process is known as ‘identifiability’ and presents two different aspects: structural or theoretical identifiability and practical identifiability. While structural identifiability is concerned with model structure alone, practical identifiability
takes into account both the quantity and quality of experimental data. In this work, we discuss the theoretical identifiability of a new model for the acetic acid fermentation process and review existing methods for this purpose.