Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review
Autor
Gómez-Melero, Sara
Caballero-Villarraso, Javier
Escribano, Begoña M.
Galvao-Carmona, Alejandro
Túnez, Isaac
Agüera Morales, Eduardo
Editor
MDPIFecha
2024Materia
Multiple sclerosisDisability
Quality of life
Cognitive impairment
Neurodegenerative diseases
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Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and sphincter disorders, which are expressed through the widely used Expanded Disability Status Scale (EDSS), other manifestations of MS have a detrimental effect on overall functioning and quality of life, such as cognitive impairment, depression, anxiety, fatigue, and pain. However, when talking about QoL, categorical definitions cannot be used because although the concept is generally understood, it is highly nuanced. Suffering from MS can significantly reduce QoL. Numerous research studies have focused on trying to identify and assess which are the elements that most affect the loss of QoL in MS people. However, in addition to the fact that the measurement of QoL can be subjective, it is very difficult to consider these elements in isolation, as they are interrelated. One such limiting factor of QoL that has been investigated is cognitive impairment (CI). This has been shown to have an impact on the lives of MS people, although the different approaches that have been taken to assess CI have evident limitations.