Listar ceiA3 por autor "d418c8b5-ba00-49f0-acb2-b98a45a4d64e"
Mostrando ítems 1-7 de 7
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Approaching In Vivo Models of Pneumococcus–Host Interaction: Insights into Surface Proteins, Capsule Production, and Extracellular Vesicles
Olaya-Abril, Alfonso; González Reyes, José Antonio; Rodríguez-Ortega, Manuel J. (MDPI, 2021)Infections caused by the Gram-positive bacterium Streptococcus pneumoniae have become a major health problem worldwide because of their high morbidity and mortality rates, especially in developing countries. This microorganism ... -
Comparative Exoproteome Analysis of Streptococcus suis Human Isolates
Prados de la Torre, Esther; Rodríguez-Franco, Antonio; Rodríguez-Ortega, Manuel J. (MDPI, 2021)The swine pathogen Streptococcus suis is a Gram-positive bacterium which causes infections in pigs, with an impact in animal health and in the livestock industry, and it is also an important zoonotic agent. During the ... -
Extracellular Vesicles from Different Pneumococcal Serotypes Are Internalized by Macrophages and Induce Host Immune Responses
Olaya-Abril, Alfonso; Prados Rosales, Rafael; González Reyes, José Antonio; Casadevall, Arturo; Pirofski, Liise-anne; Rodríguez-Ortega, Manuel J. (MDPI, 2021)Bacterial extracellular vesicles are membranous ultrastructures released from the cell surface. They play important roles in the interaction between the host and the bacteria. In this work, we show how extracellular vesicles ... -
Identification of Potential New Protein Vaccine Candidates through Pan-Surfomic Analysis of Pneumococcal Clinical Isolates from Adults
Olaya-Abril, Alfonso; Jiménez-Munguía, I.; Gómez-Gascón, Lidia; Obando, Ignacio; Rodríguez-Ortega, Manuel J. (Public Library of Science, 2013)Purified polysaccharide and conjugate vaccines are widely used for preventing infections in adults and in children against the Gram-positive bacterium Streptococcus pneumoniae, a pathogen responsible for high morbidity ... -
Proteomic analysis of goat milk kefir: profiling the fermentation-time dependent protein digestion and identification of potential peptides with biological activity
Izquierdo-González, Juan J.; Amil-Ruiz, Francisco; Zazzu, Sabina; Sánchez-Lucas, Rosa; Fuentes-Almagro, Carlos; Rodríguez-Ortega, Manuel J. (Elsevier, 2019)Kefir is a fermented dairy product, associated to health benefits because of being a probiotic and due to the presence of molecules with biological activity. In this work, we have profiled the peptide composition of goat ... -
SARS-CoV-2 Seroprevalence Study in Pediatric Patients and Health Care Workers Using Multiplex Antibody Immunoassays
Prados de la Torre, Esther; Obando, Ignacio; Vidal, Marta; Felipe, Beatriz de; Aguilar, Ruth; Izquierdo, Luis; Carolis, Carlo; Olbrich, Peter; Capilla-Miranda, Ana; Serra, Pau; Santamaria, Pere; Blanco-Lobo, Pilar; Moncunill, Gemma; Rodríguez-Ortega, Manuel J.; Dobaño, Carlota (MDPI, 2022)SARS-CoV-2 infection has become a global health problem specially exacerbated with the continuous appearance of new variants. Healthcare workers (HCW) have been one of the most affected sectors. Children have also been ... -
Search of Potential Vaccine Candidates against Trueperella pyogenes Infections through Proteomic and Bioinformatic Analysis
Galán Relaño, Ángela; Gómez-Gascón, Lidia; Rodríguez-Franco, Antonio; Luque, Inmaculada; Huerta Lorenzo, Belén; Tarradas-Iglesias, Carmen; Rodríguez-Ortega, Manuel J. (MDPI, 2020)Trueperella pyogenes is an opportunistic pathogen, responsible for important infections in pigs and significant economic losses in swine production. To date, there are no available commercial vaccines to control diseases ...