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From the Eukaryotic Molybdenum Cofactor Biosynthesis to the Moonlighting Enzyme mARC
Tejada Jiménez, M.; Chamizo-Ampudia, Alejandro; Calatrava, Victoria; Galván Cejudo, Aurora; Fernández Reyes, Emilio; Llamas Azúa, Ángel (MDPI, 2018)All eukaryotic molybdenum (Mo) enzymes contain in their active site a Mo Cofactor (Moco), which is formed by a tricyclic pyranopterin with a dithiolene chelating the Mo atom. Here, the eukaryotic Moco biosynthetic pathway ...