Listar Departamento de Anatomía y Anatomía Patológica Comparadas y Toxicología por autor "6640b2fc-dc94-4d23-acfd-82637cbc93d1"

Mostrando ítems 1-18 de 18

    • Activation of estrogen receptor-α induces gonadotroph progesterone receptor expression and action differently in young and middle-aged ovariectomized rats 

      Gordón, Ana; Aguilar, Rafaela; Garrido, José; Guil-Luna, Silvia; Millán, Yolanda; Martín de las Mulas González-Albo, Juana; Sánchez Criado, J.E. (Oxford Academic, 2009)
      BACKGROUND: We attempted to define the effect of estrogen receptor (ER)α activation on gonadotroph progesterone receptor (PR) expression (mRNA and protein) and action (GnRH-stimulated and GnRH self-priming) in short- and ...

    • Aglepristone decreases proliferation in progesterone receptor-positive canine mammary carcinomas 

      Guil-Luna, Silvia; Sánchez Céspedes, Raquel; Millán, Yolanda; De Andrés, Francisco Javier; Rollón, Eva; Domingo, Victor; Guscetti, Franco; Martín de las Mulas González-Albo, Juana (Wiley, 2011)
      Progesterone receptor (PR) antagonist aglepristone (RU534) has been used successfully for pregnancy termination and therapy of pyometra, vaginal tumors, and mammary hyperplasia in bitches and queens. All of these conditions ...

    • Captura por microdisección láser de poblaciones celulares de tumores de mama caninos para estudios de expresión génica 

      Guil-Luna, Silvia; Salguero, F.J.; Gómez-Laguna, J.; Alijojani, A.; García-Jiménez, W.; Di Palma, S.; Millán, Yolanda; Martín de las Mulas González-Albo, Juana (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)

    • Efecto anticarcinogénico de las lías del vino en la hepatocarcinogénesis inducida por dietilnitrosamina 

      Guil-Luna, Silvia; Anter, J.; Alonso Moraga, Ángeles; Martín de las Mulas González-Albo, Juana; Millán, Yolanda; Delgado de la Torre, María del Pilar; Luque de Castro, M.D.; Fernández Bedmar, Zahira Noemí (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)

    • Efectos de los antiprogestagenos sobre la proliferación del carcinoma de mama canino. Estudios in vivo e in vitro 

      Guil-Luna, Silvia (Universidad de Córdoba, Servicio de Publicaciones, 2013)
      Los tumores de mama en la especie canina representan casi la mitad de las neoplasias que afectan a la perra. Dada su elevada frecuencia, los tumores de mama caninos son importantes causas de morbilidad y mortalidad. ...

    • Expression of oestrogen and progesterone receptor in canine sebaceous gland tumours 

      Ginel, Pedro J.; Lucena, Rosario; Millán, Yolanda; Gónzalez, Sonia; Guil-Luna, Silvia; García-Monterde, J.; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Wiley, 2010)
      Sebaceous gland oestrogen α (ERα) and progesterone (PR) receptor expression was examined immunohistochemically in 26 and 32 dogs respectively with sebaceous gland hyperplasia/adenomas, epitheliomas and carcinomas, and in ...

    • Expression of the Short Form of RON/STK in Feline Mammary Carcinoma 

      Maniscalco, Lorella; Guil-Luna, Silvia; Lussich, Selina; Gattino, Francesca; Trupia, Calogero; Millán, Yolanda; Martín de las Mulas González-Albo, Juana; Sánchez Céspedes, Raquel; Saeki, Kino; Accornero, Paolo; De María, Rafaella (Sage, 2019)
      RON is a tyrosine kinase receptor activated by the macrophage-stimulating protein (MSP) ligand that is overexpressed in human breast cancer. In humans, RON protein can be present in different isoforms, and the most studied ...

    • Humanized mice for the study of immunoOncology 

      De la Rochere, Philippe; Guil-Luna, Silvia; Decaudin, Didier; Azar, Georges; Sidhu, Sukhvinder S; Piaggio, Eliane (Elsevier, 2018)
      Immunotherapy is revolutionizing cancer treatment; however, complete responses are achieved in only a small fraction of patients and tumor types. Thus, there is an urgent need for predictive preclinical models to drive ...

    • Myoepithelial cell layer integrity in canine mammary carcinoma 

      Sánchez-Céspedes, Raquel; Millán, Yolanda; Guil-Luna, Silvia; García-Monterde, J.; Reymundo, Carlos; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2011)
      The aim of this study was to determine whether the myoepithelial (ME) cell marker calponin could be used to analyze the integrity of the ME cell layer as a means of identifying canine mammary carcinoma in situ. Tissue from ...

    • Myoepithelial cells in canine mammary tumours 

      Sánchez-Céspedes, Raquel; Millán, Yolanda; Guil-Luna, Silvia; Reymundo, Carlos; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2016)
      Mammary tumours are the most common neoplasms of female dogs. Compared to mammary tumours of humans and cats, myoepithelial (ME) cell involvement is common in canine mammary tumours (CMT) of any subtype. Since ME cell ...

    • Ovarian stimulation with FSH reduces phosphorylation of gonadotrope progesterone receptor and LH secretion in the rat 

      Gordon, Ana; Garrido-Gracia, José C.; Millán, Yolanda; Martín de las Mulas González-Albo, Juana; Sánchez Criado, J.E.; Aguilar, Rafaela; Guil-Luna, Silvia (Society for Reproduction and Fertility, 2009)
      Administration of human FSH(hFSH) to cyclic rats during the dioestrous phase attenuates progesterone receptor (PR)-dependent events of the preovulatory LH surge in pro-oestrus. The increased bioactivity of the putative ...

    • Potencial anti-hepatocarcinogénico y de desmetilación de la hesperidina: un polifenol presente en los cítricos 

      Fernández Bedmar, Zahira Noemí; Alonso Moraga, Ángeles; Martín de las Mulas González-Albo, Juana; Millán, Yolanda; Guil-Luna, Silvia (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)

    • Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma 

      Guil-Luna, Silvia; Stenvang, Jan; Brünner, Nils; De Andrés, Francisco Javier; Sánchez Céspedes, Raquel; Millán, Yolanda; Martín de las Mulas González-Albo, Juana (BioMed Central, 2014)
      Background: Progesterone receptors play a key role in the development of canine mammary tumours, and recent research has focussed on their possible value as therapeutic targets using antiprogestins. Cloning and sequencing of ...

    • Progesterone Receptor Isoform Analysis by Quantitative Real-Time Polymerase Chain Reaction in Formalin-Fixed, Paraffin-Embedded Canine Mammary Dysplasias and Tumors 

      Guil-Luna, Silvia; Stenvang, Jan; Brünner, Nils; Sánchez Céspedes, Raquel; Millán, Yolanda; Gómez-Laguna, J.; Martín de las Mulas González-Albo, Juana (Sage, 2014)
      Cloning and sequencing of the progesterone receptor gene in dogs have revealed 2 isoforms, A and B, transcribed from a single gene. Distribution of isoforms A and B in canine mammary lesions has hitherto been investigated ...

    • Prognostic impact of neoadjuvant aglepristone treatment in clinicopathological parameters of progesterone receptor-positive canine mammary carcinomas 

      Guil-Luna, Silvia; Millán, Yolanda; De Andrés, Francisco Javier; Rollón, Eva; Domingo, Victor; García-Macías, Javier; Martín de las Mulas González-Albo, Juana (Wiley, 2017)
      Neoadjuvant treatment of canine mammary carcinomas with the progesterone receptor (PR) antagonist aglepristone has a PR expression-related inhibiting effect on proliferation index (PI). The aim of this study was to evaluate ...

    • Red and White Wine Lees show inhibitory effects on liver carcinogenesis 

      Fernández Bedmar, Zahira Noemí; Anter, J.; Alonso Moraga, Ángeles; Delgado de la Torre, María del Pilar; Luque de Castro, M.D.; Millán, Yolanda; Sánchez-Frías, Marina; Guil-Luna, Silvia (Wiley, 2019-05)
      Scope: Wine has shown anticarcinogenic benefits in hepatocarcinoma and polyphenols seem to be responsible for these effects. Wine lees are the sediments produced during fermentation and they endow wine with organoleptic ...

    • Sex Steroid Hormones and Tumors in Domestic Animals 

      Millán, Yolanda; Guil-Luna, Silvia; Sánchez-Céspedes, Raquel; Martín de las Mulas González-Albo, Juana (Intech, 2013)
      Sex steroid hormones play a role in the development and control of animal tumours, particularly in those arising in their target organs. Due to their incidence and prevalence, mammary tumours of female dogs and cats are ...

    • Use of CD10 as a marker of canine mammary myoepithelial cells 

      Sánchez-Céspedes, Raquel; Suárez-Bonnet, Alejandro; Millán, Yolanda; Guil-Luna, Silvia; Reymundo, Carlos; Herráez, Pedro; Espinosa de los Monteros, Antonio; Martín de las Mulas González-Albo, Juana (Elsevier, 2013)
      CD10 is an important cell marker in the diagnosis of acute lymphoblastic leukaemia and of breast myoepithelial (ME) cells in humans. The objective of this study was to assess the value of CD10 as a marker of canine ME cells ...