Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 191-210 de 289
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Molecular and Clinical Implications of Somatostatin Receptor Profile and Somatostatin Analogues Treatment in Oral Cavity Squamous Cell Carcinoma
(MDPI, 2021)Oral squamous cell carcinoma (OSCC) incidence has increased by 50% over the last decade. Unfortunately, surgery and adjuvant radiotherapy and chemotherapy are still the mainstream modality of treatment, underscoring the ... -
Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly
(Nature Research, 2015)Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels ... -
Molecular Research on Stress Responses in Quercus spp.: From Classical Biochemistry to Systems Biology through Omics Analysis
(MDPI, 2021)The genus Quercus (oak), family Fagaceae, comprises around 500 species, being one of the most important and dominant woody angiosperms in the Northern Hemisphere. Nowadays, it is threatened by environmental cues, which are ... -
Molecular, cellular and anatomopathological study of oral cavity tumors
(Universidad de Córdoba, UCOPress, 2022)Oral cavity squamous cell carcinoma (OSCC) continues to be an aggressive disease and a global challenge with a 5-year survival rate of 60%. Depending on the risk factors, surgery and adjuvant radiotherapy +/- chemotherapy ... -
Molecular, cellular and endocrine-metabolic factors involved in the pathological interaction between obesity and prostate cancer: Therapeutic role of metformin
(Universidad de Córdoba, UCOPress, 2017)La próstata es una glándula exocrina con forma oval, localizada entre la vejiga y el pene y con el tamaño de una nuez. Esta glándula representa un órgano importante dentro de los sistemas urinarios y reproductivos ya que ... -
Morphofunctional and Molecular Assessment of Nutritional Status in Head and Neck Cancer Patients Undergoing Systemic Treatment: Role of Inflammasome in Clinical Nutrition
(MDPI, 2022)Malnutrition in patients with head and neck cancer is frequent, multifactorial and widely associated with clinical evolution and prognosis. Accurate nutritional assessments allow for early identification of patients at ... -
Multi-organ increase in Norepinephrine levels after central leptin administration and diet-induced obesity
(MDPI, 2023)Autonomic innervation is important to regulate homeostasis in every organ of the body. The sympathetic nervous system controls several organs associated with metabolism and reproduction, including adipose tissue, the liver, ... -
Los Murciélagos del complejo Hundidero-Gato
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Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-kB Pathways
(MDPI, 2017)Twenty-eight neoflavonoids have been prepared and evaluated in vitro against HIV-1. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase reporter gene. Inhibition of HIV ... -
Neuroprotective effect of S-allyl cysteine on an experimental model of multiple sclerosis: Antioxidant effects
(Elsevier, 2018)S-allyl cysteine (SAC), has shown itself to performance important activity as a neuroprotective agent. This action is prompted by antioxidative activity. The aim of this study was to evaluate the neuroprotective effect of ... -
Neuroprotective Effects of Betulinic Acid Hydroxamate in Intraventricular Hemorrhage-Induced Brain Damage in Immature Rats
(MDPI, 2022)Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. We aimed to study in an IVH model in immature rats the neuroprotective effect of ... -
Non psychotropic cannabinoids for the treatment of inflammatory diseases
(Universidad de Córdoba, UCOPress, 2020)Medicinal cannabis and purified cannabinoids have garnered worldwide attention since millions of patients can benefit from their medical properties. Over the past few years, the endocannabinoid system (ECS) has emerged as ... -
Non-Coding RNAs in Kidney Diseases: The Long and Short of Them
(MDPI, 2021)Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a miscellaneous group of largely unknown RNA transcripts, which contain the ... -
Novel diagnostic biomarkers and therapeutic options for neuroendocrine tumors
(Universidad de Córdoba, UCOPress, 2019)Neuroendocriene tumoren (NET) vormen een heterogene groep van zeldzaam voorkomende, langzaam groeiende tumoren. NET ontstaan vanuit enterochromaffine cellen. De jaarlijkse incidentie van NET is progressief toegenomen in ... -
Novel molecular insights on the role of splicing dysregulation in cancer
(Universidad de Córdoba, UCOPress, 2022)Cancer and tumoral diseases represent one of most serious and complicated public health problems, being one of the leading causes of death in the world. The remarkable variety across cancer types, and the heterogeneity ... -
Novel regulatory mechanisms of Kiss1 neurons during reproductive axis development and in conditions of metabolic stress: Analysis of the roles of microRNAs and elements of the secretory pathway
(Universidad de Córdoba, UCOPress, 2023)Reproduction is indispensable for the perpetuation of the species. Therefore, it is safeguarded by a sophisticated network of regulatory mechanisms that ultimately controls the reproductive function by modulating the ... -
Novel regulatory pathways in the central control of puberty: analysis of the role of ceramide signaling and Mkrn3/miR-30b system
(Universidad de Córdoba, UCOPress, 2019) -
Nuevos mecanismos de control de la proteína supresora de tumores FBXW7 mediados por la quinasa DYRK2
(Universidad de Córdoba, UCOPress, 2023)The systems responsible for protein homeostasis play a fundamental role in the development of tumors. These systems recognize and degrade incomplete, misfolded proteins or act as control mechanisms for cellular processes. ... -
Nuevos triterpenos hidroxamatos como activadores de HIF. Implicaciones terapéuticas
(Universidad de Córdoba, UCOPress, 2021)El factor inducible por hipoxia (HIF) se estabiliza durante los procesos inflamatorios asociados a un gran número de patologías, produciendo cambios en la expresión génica con un profundo impacto en el microambiente tisular, ... -
Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue
(Society for Endocrinology, 2013)There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...