Departamento de Biología Celular, Fisiología e Inmunología
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CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice
(Springer, 2022)Cytochrome b5 reductase 3 (CYB5R3) overexpression activates respiratory metabolism and exerts prolongevity effects in transgenic mice, mimicking some of the salutary effects of calorie restriction. The aim of our study was ... -
Determination of new DYRK2 functions in response to genotoxic stress
(Universidad de Córdoba, UCOPress, 2022)Cancer is a complex disease enhanced by alterations in signaling pathways. In fact, DNA damage response (DDR) pathways play a key role in cancer development when they are deregulated. DDR pathways induce a cellular response ... -
Papel de la Citocromo b5 reductasa-3 (CYB5R3) y del componente graso de la dieta en la fisiología y el envejecimiento del músculo esquelético
(Universidad de Córdoba, UCOPress, 2022)El envejecimiento es el declive progresivo dependiente del tiempo que viene acompañado de una disminución de la fertilidad y del aumento de la susceptibilidad del organismo a amenazas tanto endógenas como externas. A lo ... -
Identification of Novel Markers and Molecular Mechanisms with Diagnostic, Prognostic, and Therapeutic Potential in Brain Tumors
(Universidad de Córdoba, UCOPress, 2022)Primary brain tumors represent a highly variable and heterogeneous group of neoplasms (~150 different types) that includes non-malignant and malignant tumors. The most frequent malignant brain tumors are gliomas (representing ... -
CCN2 Binds to Tubular Epithelial Cells in the Kidney
(MDPI, 2022)Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ...