Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 233-252 de 286
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Rab18 drift in lipid droplet and endoplasmic reticulum interactions of adipocytes under obesogenic conditions
(MDPI, 2023)The adipose tissue stores excess energy in the form of neutral lipids within adipocyte lipid droplets (LDs). The correct function of LDs requires the interaction with other organelles, such as the endoplasmic reticulum ... -
Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
(Public Libray of Science (PLOS), 2011)Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ... -
Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity
(PLOS, 2011)Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ... -
Rab18 is reduced in pituitary tumors cusing acromegaly and its overexpression reverts growth hormone hypersecretion
(Oxford Academic, 2008)Context: Rab proteins regulate the sequential steps of intracellular membrane transport. Alterations of these GTPases and their associated proteins are emerging as the underlying cause for several human diseases involving ... -
Regulación de la lisis de células de melanoma mediante coestimuladores y receptores inhibidores de la citotoxicidad
(Universidad de Córdoba, Servicio de Publicaciones, 2004)El sistema inmune a través de la inmunidad celular juega un papel importante en el reconocimiento y eliminación de células tumorales. La respuesta inmune celular requiere un reconocimiento específico del tumor seguido de ... -
Regulación de las gotas lipídicas en adipocitos: papel de RAB 18 y caracterización de su interactoma
(Universidad de Córdoba, Servicio de Publicaciones, 2014)El tejido adiposo (TA) juega un papel fundamental en la gestión de las reservas energéticas y como órgano endocrino productor de adipoquinas, que regulan la ingesta y la homeostasis energética, la inmunidad y la función ... -
Regulación fisiológica mitocondrial y de señalización autofágica a través de intervenciones nutricionales con diferentes fuentes lipídicas y antioxidantes
(Universidad de Córdoba, UCOPress, 2018)1. Introducción o motivación de la tesis La autofagia es un proceso intracelular por el que se degradan partes de citoplasma, orgánulos como mitocondrias y peroxisomas, agregados proteicos y agentes infecciosos, por acción ... -
Regulation of coenzyme Q biosynthesis through nutritional and pharmacological interventions
(Universidad de Córdoba, UCOPress, 2017)El coenzima Q (Q) es una benzoquinona prenilada presente en todos los organismos eucariotas. Se localiza principalmente en la mitocondria pero está presente en todas las membranas celulares. Esta molécula, además de ... -
Regulation of post-translational modifications with pharmacological intervention: autoimmune diseases and cancer
(Universidad de Córdoba, UCOPress, 2022)Post-Translational Modifications are key elements within the cell signalling pathways. These key events promptly reprogram protein's behaviour in presence of environmental alterations in a highly dynamic manner acting as ... -
Relaciones dentro de la subfamilia Papilionoideae a la luz de los datos palinológicos
(Universidad de Córdoba, Facultad de Ciencias, Departamento de Botánica; Asociación de Palinólogos de Lengua Española, 1985)En este t rabajo se realiza un análisis numérico de la semejanza pol ínica de 216 especies de Leguminosae de Andalucía Occi de ntal ~ dichas semejanzas se representan según un dendrograma y a partir del cual se comentan l ... -
Role and regulation of the novel splicing variants sst5TMD4 and In1-ghrelin in breast cancer
(Universidad de Córdoba, UCOPress, 2016)El cáncer, en sus múltiples formas, es uno de los mayores retos a los que se enfrenta la sociedad actual. Una de las mayores limitaciones en la investigación del cáncer es la gran heterogeneidad existente entre las diferentes ... -
Role of Endogenous Cortistatin in the Regulation of Ghrelin System Expression at Pancreatic Level under Normal and Obese Conditions
(Public Library Of Science (PLOS), 2013)Ghrelin-system components [native ghrelin, In1-ghrelin, Ghrelin-O-acyltransferase enzyme (GOAT) and receptors (GHS-Rs)] are expressed in a wide variety of tissues, including the pancreas, where they exert different ... -
Role of splicing process alterations in the appearance of endocrine-metabolic diseases and tumor pathologies
(Universidad de Córdoba, UCOPress, 2019)Global human health is currently threatened by highly prevalent diseases such as obesity, diabetes and cancer. A common hallmark shared by these endocrine-metabolic and tumor diseases is the consistent alteration of the ... -
Role of SST, CORT and ghrelin, and its receptors at the endocrine pancreas
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Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury
(Wiley, 2022)Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ... -
Semaglutide improves liver steatosis and de novo lipogenesis markers in obese and type-2-diabetic mice with metabolic-dysfunction-associated steatotic liver disease
(MDPI, 2024)Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a prevalent clinical condition associated with elevated morbidity and mortality rates. Patients with MASLD treated with semaglutide, a glucagon-like ... -
Senescence of cytotoxic lymphocytes: functional changes and role of CMV
(Universidad de Córdoba, UCOPress, 2017)1. Introducción o motivación de la tesis. Inmunosenescencia es el deterioro de la inmunidad como resultado de los cambios asociados a la edad. Estos cambios relacionados con la edad tales como alteraciones del fenotipo y ... -
Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue
(Nature Research, 2017)During their lifetime, females are subjected to different nutritional and hormonal factors that could increase the risk of obesity and associated comorbidities. From early postnatal periods until the postmenopausal phase, ... -
Simple autosomic recessive inheritance of cataplexy in fighting bulls
(Universidad de Córdoba, Servicio de Publicaciones, 1983)The problem of collapsing in the fighting bull breed was conceived from a scientific point of view beginning in the thirties when different experts (Castejón y Martínez de Arizala, Peralbo, González Garcia, etc. (8) ) tried ... -
Sistemas de detección ultrasensible de moléculas de distinta naturaleza para la detección temprana del cáncer
(Universidad de Córdoba, UCOPress, 2022)La técnica ELISA (del inglés “enzyme-linked immunosorbent assay”) es el método de rutina más utilizado y fiable para la detección de marcadores proteicos relevantes en la asistencia sanitaria. Aumentar la sensibilidad de ...