ListarDepartamento de Biología Celular, Fisiología e Inmunología por tema "Autophagy"
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CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice
(Springer, 2022)Cytochrome b5 reductase 3 (CYB5R3) overexpression activates respiratory metabolism and exerts prolongevity effects in transgenic mice, mimicking some of the salutary effects of calorie restriction. The aim of our study was ... -
Mechanisms of longevity extension and healthy aging by over-expression of cytochrome b5 reductase 3
(Universidad de Córdoba, UCOPress, 2021)Introduction. Aging is a natural time-dependent process characterized by the accumulation of damage in cellular structures that compromises cellular and tissue function leading ultimately to the death of the organism. ... -
The ghrelin O-acyltransferase–ghrelin system reduces TNF-α-induced apoptosis and autophagy in human visceral adipocytes
(SpringerLink, 2012)Aims/hypothesis Proinflammatory and proapoptotic cytokines such as TNF-α are upregulated in human obesity. We evaluated the association between ghrelin isoforms (acylated and desacyl ghrelin) and TNF-α in obesity and ... -
The Role of Autophagy in White Adipose Tissue Function: Implications for Metabolic Health
(MDPI, 2020)White adipose tissue (WAT) is a highly adaptive endocrine organ that continuously remodels in response to nutritional cues. WAT expands to store excess energy by increasing adipocyte number and/or size. Failure in WAT ...