ListarDepartamento de Biología Celular, Fisiología e Inmunología por tema "Chronic kidney disease"

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    • Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice 

      Carmona Hidalgo, Beatriz; García-Martín, Adela; Muñoz, Eduardo; González-Mariscal, Isabel (MDPI, 2021)
      Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD). CBD-based medicinal drugs have been approved for over a lustrum, and a boom in the commercialization of CBD products started in ...

    • Hematuria Is Associated with More Severe Acute Tubulointerstitial Nephritis 

      Esteras, Raquel; Fox, Jonathan G.; Geddes, Colin C.; Mackinnon, Bruce; Ortiz, Alberto; Moreno, Juan Antonio (MDPI, 2020)
      Acute tubulointerstitial nephritis (ATIN) is a common cause of acute kidney injury. Although haematuria is a risk factor for the development of renal disease, no previous study has analyzed the significance of haematuria ...

    • Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities 

      Opazo-Ríos, Lucas; Mas, Sebastián; Marín-Royo, Gema; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, J. (MDPI, 2020)
      Lipotoxicity is characterized by the ectopic accumulation of lipids in organs different from adipose tissue. Lipotoxicity is mainly associated with dysfunctional signaling and insulin resistance response in non-adipose ...

    • Non-Coding RNAs in Kidney Diseases: The Long and Short of Them 

      Moreno, Juan Antonio; Hamza, Eya; Guerrero-Hue, Melania; Rayego-Mateos, Sandra; García-Caballero, Cristina; Vallejo-Mudarra, Mercedes; Metzinger, Laurent; Metzinger-Le Meuth, Valérie (MDPI, 2021)
      Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a miscellaneous group of largely unknown RNA transcripts, which contain the ...

    • Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy 

      Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; Guerrero-Hue, Melania; García-Caballero, Cristina; Vázquez-Carballo, Cristina; Mas, Sebastián; Sanz, Ana Belén; Herencia, Carmen; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, J. (MDPI, 2020)
      Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting in elevated cost for public health systems. DN is the main cause of chronic kidney disease (CKD) and its incidence increases the ...