ListarDepartamento de Biología Celular, Fisiología e Inmunología por tema "Therapeutic targets"
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Identification of novel biomarkers and therapeutic targets in the pathological interaction between the dysregulation of the endocrinemetabolic system and prostate cancer
(Universidad de Córdoba, UCOPress, 2022)Obesity (OB) is a metabolic chronic disease with a growing incidence and elevated morbidities and mortality [1, 2]. OB is also associated with elevated economic costs for the health systems representing a worldwide public ... -
Identification of novel endocrine-metabolic and splicing machinery factors with diagnostic, prognostic and/or therapeutic potential in prostate cancer
(Universidad de Córdoba, UCOPress, 2020)Prostate cancer (PCa) is the tumor pathology with the highest incidence among men in developed countries and represents one of the main causes of cancer-related death in this group. Despite the advances achieved during the ... -
Implication of the alternative splicing process in the development of hepatocelular carcinoma
(Universidad de Córdoba, UCOPress, 2021)Liver cancer represents a complex and heterogeneous pathology that encompasses several types of malignant tumors with unfavorable characteristics and prognosis, including hepatocellular carcinoma or hepatocarcinoma (HCC). ... -
Molecular, cellular and anatomopathological study of oral cavity tumors
(Universidad de Córdoba, UCOPress, 2022)Oral cavity squamous cell carcinoma (OSCC) continues to be an aggressive disease and a global challenge with a 5-year survival rate of 60%. Depending on the risk factors, surgery and adjuvant radiotherapy +/- chemotherapy ... -
Novel molecular insights on the role of splicing dysregulation in cancer
(Universidad de Córdoba, UCOPress, 2022)Cancer and tumoral diseases represent one of most serious and complicated public health problems, being one of the leading causes of death in the world. The remarkable variety across cancer types, and the heterogeneity ... -
Peptides derived from the extracellular domain of the somatostatin receptor splicing variant 1 SST5TMD4 increase malignancy in multiple cancer cell types
(Elsevier, 2019)Extracellular fragments derived from plasma membrane receptors can play relevant roles in the development/progression of tumor pathologies, thereby offering novel diagnostic or therapeutic opportunities. The truncated ...