Listar por autor "ff922cf9-a31c-43d9-86a4-9b0c45cf5149"

Mostrando ítems 1-5 de 5

    • A Cannabigerol Derivative Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis 

      Carrillo-Salinas, Francisco J.; Navarrete, Carmen; Mecha, Miriam; Feliú, Ana; Collado, Juan A.; Cantarero, Irene; Bellido, María L.; Muñoz, Eduardo; Guaza, Carmen (PLOS, 2014)
      Phytocannabinoids that do not produce psychotropic effects are considered of special interest as novel therapeutic agents in CNS diseases. A cannabigerol quinone, the compound VCE-003, has been shown to alleviate symptoms ...

    • Cannabidiol and Other Cannabinoids in Demyelinating Diseases 

      Navarrete, Carmen; García-Martín, Adela; Rolland, Alain; DeMesa, Jim; Muñoz, Eduardo (MDPI, 2021)
      A growing body of preclinical evidence indicates that certain cannabinoids, including cannabidiol (CBD) and synthetic derivatives, may play a role in the myelinating processes and are promising small molecules to be developed ...

    • EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice 

      García-Martín, Adela; Navarrete, Carmen; Garrido Rodríguez-Córdoba, Martín; Prados, María E.; Caprioglio, Diego; Appendino, Giovanni; Muñoz, Eduardo (Elsevier, 2021)
      Some cannabinoids showed anti-inflammatory and antifibrotic activities. EHP-101 is an oral lipidic formulation of the novel non-psychotropic cannabidiol aminoquinone VCE-004.8, which showed antifibrotic activity in murine ...

    • Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses 

      Appel, Kurt; Muñoz, Eduardo; Navarrete, Carmen; Cruz Teno, Cristina; Biller, Andreas; Thiemann, Eva (MDPI, 2018)
      Immulina®, a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis (Spirulina) is a potent activator of innate immune cells. On the other hand, it is well documented that Spirulina ...

    • Metabolic shift underlies tumor progression and immune evasion in S-nitrosoglutathione reductase-deficient cancer 

      Mena-Osuna, Rafael; Mantrana, Ana; Guil-Luna, Silvia; Sánchez, María-Teresa; Navarrete, Carmen; Morales-Ruiz, T.; Rivas-Crespo, Aurora; Toledano-Fonseca, Marta; García-Ortíz, María Victoria; García Jurado, Gema; Gómez-España, M. Auxiliadora; González Fernández, Rafael A.; Villar, Carlos; Medina Fernández, Francisco Javier; Villalba, José Manuel; Aranda Aguilar, Enrique; Rodríguez-Ariza, Antonio (Wiley, 2023)
      S-nitrosoglutathione reductase (GSNOR) is a denitrosylase enzyme that has been suggested to play a tumor suppressor role, although the mechanisms responsible are still largely unclear. In this study, we show that GSNOR ...