ListarDepartamento de Genética por tema "TET dioxygenases"

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    • DNA methylation editing by CRISPR-guided excision of 5-methylcytosine 

      Devesa-Guerra, I.; Morales-Ruiz, T.; Pérez Roldán, Juan; Parrilla-Doblas, Jara; Dorado León, Macarena; García-Ortiz, M.V.; Ariza, Rafael R.; Roldán-Arjona, Teresa (Elsevier, 2020)
      Tools for active targeted DNA demethylation are required to increase our knowledge about regulation and specific functions of this important epigenetic modification. DNA demethylation in mammals involve TET-mediated oxidation ...