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Phosphorus restriction does not prevent the increase in fibroblast growth factor 23 elicited by high fat diet
(Public Library of Science, 2018)
This
study
was
designed
to evaluate
the
influence
of phosphorus
(P)
restriction
on
the
dele-
terious
effects
of high
fat
diets
on
mineral
metabolism.
Twenty-four
rats
were
allotted
to 3
groups
(n ...
Energy-dense diets increase FGF23, lead to phosphorus retention and promote vascular calcifications in rats
(Nature.com, 2016)
Rats with normal renal function (Experiment 1, n = 12) and uninephrectomized (1/2Nx) rats
(Experiment 2, n = 12) were fed diets with normal P (NP) and either normal (NF) or high fat (HF).
Rats with intact renal function ...
Oral Acid Load Down-Regulates Fibroblast Growth Factor 23
(MDPI, 2022)
Increased dietary acid load has a negative impact on health, particularly when renal function is compromised. Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that is elevated during renal failure. The ...