Listar Departamento de Sanidad Animal por autor "f1c725b0-7cd1-4ff0-b9d6-910cdca3fcb7"
Mostrando ítems 1-10 de 10
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A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
Molina Hernández, Verónica; Ruiz-Campillo, María Teresa; Martínez-Moreno, Francisco Javier; Buffoni Perazzo, Leandro; Martínez-Moreno, Álvaro; Zafra Leva, Rafael; Escamilla, Alejandro; Pérez Caballero, Raúl; Pérez Arévalo, José (MDPI, 2021)Fasciolosis is an important economic disease of livestock. There is a global interest in the development of protective vaccines since current anthelmintic therapy is no longer sustainable. A better knowledge of the ... -
Cambios celulares y moleculares en el perioteneo asociados con la patología hepática en fases tempranas de la infección con fasciola hepática en ovejas
Molina Hernández, Verónica; Ruiz-Campillo, María Teresa; Escamilla, Alejandro; Pérez, José; Martínez-Moreno, Álvaro; Cwiklinski, Krystyna; Stevenson, Michael; Donnelly, Sheila; Dalton, John P. (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Caracterización de macrófagos peritoneales de ovejas en fases tempranas de infección experimental con fasciola hepática
Zafra Leva, Rafael; Pacheco, I.L.; Escamilla, Alejandro; Caballero, R.; Buffoni Perazzo, Leandro; Molina Hernández, Verónica; Martínez-Moreno, Álvaro; Pérez, José; Ruiz-Campillo, María Teresa (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica
Ruiz-Campillo, María Teresa; Molina-Hernández, Verónica; Bautista, María José; Pacheco, I.L.; Zafra, Rafael; Buffoni Perazzo, Leandro; Martínez-Moreno, Francisco Javier; Martínez Moreno, Álvaro; Pérez, José (Springer, 2020)Fasciola hepatica has been shown to have a high capacity for immunomodulation of the host response, making the development of protective vaccines extremely difficult. One of these immunomodulation mechanisms is the impairment ... -
Distribución de linfocitos FOXP3 reguladores en hígado y nódulos linfáticos de ovejas y cabras infectadas con fasciola hepática
Escamilla, Alejandro; Zafra Leva, Rafael; Bautista Pérez, María José; Pacheco, I.L.; Ruiz-Campillo, María Teresa; Martínez-Moreno, Álvaro; Molina Hernández, Verónica; Pérez, José (Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Efficacy of a multivalent vaccine against Fasciola hepatica infection in sheep
Zafra, Rafael; Buffoni Perazzo, Leandro; Pérez Caballero, Raúl; Molina-Hernández, Verónica; Ruiz-Campillo, María Teresa; Pérez, José; Martínez Moreno, Álvaro; Martínez-Moreno, Francisco Javier (Springer, 2021)In this work we report the protection found in a vaccination trial performed in sheep with two different vaccines composed each one by a cocktail of antigens (rCL1, rPrx, rHDM and rLAP) formulated in two different adjuvants ... -
Fasciola hepatica induces Foxp3 T cell, proinflammatory and regulatory cytokine overexpression in liver from infected sheep during early stages of infection
Pacheco, Isabel; Abril, Nieves; Zafra, Rafael; Molina-Hernández, Verónica; Morales‑Prieto2, Noelia; Bautista, M.J.; Ruiz-Campillo, María Teresa; Pérez Caballero, Raúl; Martínez Moreno, Álvaro; Pérez, José (Springer, 2018)The expression of T regulatory cells (Foxp3), regulatory (interleukin [IL]-10 and transforming growth factor beta [TGF-β]) and proinflammatory (tumor necrosis factor alpha [TNF-α] and interleukin [IL]-1β) cytokines was ... -
Fasciola hepatica primoinfections and reinfections in sheep drive distinct Th1/Th2/Treg immune responses in liver and hepatic lymph node at early and late stages
Ruiz-Campillo, María Teresa; Barrero‑Torres, Diana María; Abril, Nieves; Pérez, José; Zafra Leva, Rafael; Buffoni Perazzo, Leandro; Martínez Moreno, Álvaro; Martínez-Moreno, Francisco Javier; Molina-Hernández, Verónica (Springer, 2023)The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of sheep primoinfected ... -
Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development
Flores Velazquez, Luis Miguel; Ruiz-Campillo, María Teresa; Herrera-Torres, Guillem; Martínez Moreno, Álvaro; Martínez-Moreno, Francisco Javier; Zafra, Rafael; Buffoni Perazzo, Leandro; Rufino-Moya, Pablo José; Molina-Hernández, Verónica; Pérez, José (Frontiers, 2023)Fasciola hepatica has a worldwide distribution causing important economic losses in animal production industry. Human fasciolosis is considered an emerging zoonosis in areas of Andean America, Asia, and Africa. The control ... -
Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
Ruiz-Campillo, María Teresa; Molina Hernández, Verónica; Escamilla, Alejandro; Stevenson, Michael; Pérez, José; Martínez-Moreno, Álvaro; Donnelly, Sheila; Dalton, John P.; Cwiklinski, Krystyna (Nature, 2017)Immune signatures of sheep acutely-infected with Fasciola hepatica, an important pathogen of livestock and humans were analysed within the peritoneal compartment to investigate early infection. Within the peritoneum, F. ...