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Cambios celulares y moleculares en el perioteneo asociados con la patología hepática en fases tempranas de la infección con fasciola hepática en ovejas
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)
Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica
(Nature, 2017)
Immune signatures of sheep acutely-infected with Fasciola hepatica, an important pathogen of
livestock and humans were analysed within the peritoneal compartment to investigate early infection.
Within the peritoneum, F. ...
Distribución de linfocitos FOXP3 reguladores en hígado y nódulos linfáticos de ovejas y cabras infectadas con fasciola hepática
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)
Caracterización de macrófagos peritoneales de ovejas en fases tempranas de infección experimental con fasciola hepática
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016)
A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
(MDPI, 2021)
Fasciolosis is an important economic disease of livestock. There is a global interest in the development of protective vaccines since current anthelmintic therapy is no longer sustainable. A better knowledge of the ...
Fasciola hepatica primoinfections and reinfections in sheep drive distinct Th1/Th2/Treg immune responses in liver and hepatic lymph node at early and late stages
(Springer, 2023)
The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the
transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of sheep primoinfected ...
Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica
(Springer, 2020)
Fasciola hepatica has been shown to have a high capacity for immunomodulation of the host response, making the development of protective vaccines extremely difficult. One of these immunomodulation mechanisms is the impairment ...
Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development
(Frontiers, 2023)
Fasciola hepatica has a worldwide distribution causing important economic losses in animal production industry. Human fasciolosis is considered an emerging zoonosis in areas of Andean America, Asia, and Africa. The control ...
Evaluation of Th1/Th2, regulatory cytokines and transcriptional factor FoxP3 in sheep immunized with a partially protective and non-protective vaccine and challenged with Fasciola hepatica
(BMC (Springer), 2024)
Gene expression for Th1/Th2 cytokines (IL-4 and IFN-ɣ), regulatory cytokines (TGF-β and IL-10) and the transcriptional factor FoxP3 was analyzed in the liver and hepatic lymph nodes (HLN) from sheep immunized with partially ...
Fasciola hepatica induces Foxp3 T cell, proinflammatory and regulatory cytokine overexpression in liver from infected sheep during early stages of infection
(Springer, 2018)
The expression of T regulatory cells (Foxp3), regulatory (interleukin [IL]-10 and transforming growth factor beta [TGF-β]) and proinflammatory (tumor necrosis factor alpha [TNF-α] and interleukin [IL]-1β) cytokines was ...