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The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation
dc.contributor.author | Martínez-Macías, M.I. | |
dc.contributor.author | Córdoba-Cañero, Dolores | |
dc.contributor.author | Rodríguez Ariza, Rafael | |
dc.contributor.author | Roldán-Arjona, Teresa | |
dc.date.accessioned | 2018-05-02T12:55:51Z | |
dc.date.available | 2018-05-02T12:55:51Z | |
dc.date.issued | 2013 | |
dc.identifier.uri | http://hdl.handle.net/10396/16563 | |
dc.description.abstract | Background: Active DNA demethylation in plants is initiated by 5-meC DNA glycosylases of the ROS1/DME family and continued through a base excision repair pathway. Results: XRCC1 stimulates ROS1-initiated demethylation and is required for efficient processing of post-excision intermediates. Conclusion: XRCC1 functions at several stages during active DNA demethylation. Significance: This study identifies a new component of the active DNA demethylation pathway in Arabidopsis. | es_ES |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | JBC | es_ES |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | es_ES |
dc.source | The Journal of Biological Chemistry 288 (8), 5496-5505 (2013) | es_ES |
dc.subject | Arabidopsis | es_ES |
dc.subject | DNA | es_ES |
dc.subject | Chromosomes | es_ES |
dc.title | The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1074/jbc.M112.427617 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |