The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation

dc.contributor.author	Martínez-Macías, M.I.
dc.contributor.author	Córdoba-Cañero, Dolores
dc.contributor.author	Rodríguez Ariza, Rafael
dc.contributor.author	Roldán-Arjona, Teresa
dc.date.accessioned	2018-05-02T12:55:51Z
dc.date.available	2018-05-02T12:55:51Z
dc.date.issued	2013
dc.identifier.uri	http://hdl.handle.net/10396/16563
dc.description.abstract	Background: Active DNA demethylation in plants is initiated by 5-meC DNA glycosylases of the ROS1/DME family and continued through a base excision repair pathway. Results: XRCC1 stimulates ROS1-initiated demethylation and is required for efficient processing of post-excision intermediates. Conclusion: XRCC1 functions at several stages during active DNA demethylation. Significance: This study identifies a new component of the active DNA demethylation pathway in Arabidopsis.	es_ES
dc.format.mimetype	application/pdf	es_ES
dc.language.iso	eng	es_ES
dc.publisher	JBC	es_ES
dc.rights	https://creativecommons.org/licenses/by-nc-nd/4.0/	es_ES
dc.source	The Journal of Biological Chemistry 288 (8), 5496-5505 (2013)	es_ES
dc.subject	Arabidopsis	es_ES
dc.subject	DNA	es_ES
dc.subject	Chromosomes	es_ES
dc.title	The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.relation.publisherversion	http://dx.doi.org/10.1074/jbc.M112.427617	es_ES
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es_ES