Listar DGen-Artículos, capítulos... por autor "ba2150b1-ce91-49f3-ab1f-cc94b74a3099"
Mostrando ítems 1-11 de 11
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A genome-wide association study of mare fertility in the Pura Raza Español horse
Laseca, Nora; Demyda-Peyrás, S.; Valera Córdoba, M.; Ramón, M.; Escribano, Begoña M.; Perdomo-González, Davinia I.; Molina, Antonio (Elsevier, 2022)Despite the economic importance of fertility for the horse industry, few efforts have been made to achieve a better understanding of the genetic mechanisms underlying its control. This is probably due to the difficulty of ... -
Análisis genético de la infertilidad y subfertilidad en équidos: análisis de asociación de genoma completo en yeguas de Pura Raza Española.
Laseca, Nora (Universidad de Córdoba, UCOPress, 2023)Esta Tesis Doctoral tiene como objetivos, en primer lugar, determinar la posible asociación entre regiones genómicas de homocigosidad con la reducción de la fertilidad y analizar el efecto de la depresión consanguínea ... -
Estimation of the Genetic Components of (Co)variance and Preliminary Genome-Wide Association Study for Reproductive Efficiency in Retinta Beef Cattle
Jiménez, José María; Morales Cid, Rosa; Menéndez-Buxadera, A.; Demyda-Peyrás, S.; Laseca, Nora; Molina, Antonio (MDPI, 2023)In this study, we analyzed the variation of reproductive efficiency, estimated as the deviation between the optimal and real parity number of females at each stage of the cow’s life, in 12,554 cows belonging to the Retinta ... -
Fine-Scale Analysis of Runs of Homozygosity Islands Affecting Fertility in Mares
Laseca, Nora; Molina Alcalá, Antonio; Ramón, M.; Valera, M.; Azcona, Florencia; Encina, Ana; Demyda-Peyrás, S. (Frontiers, 2022)The loss of genetic variability in livestock populations bred under strict selection processes is a growing concern, as it may lead to increased inbreeding values and lower fertility, as a consequence of the “inbreeding ... -
Fine-tuning genomic and pedigree inbreeding rates in equine population with a deep and reliable stud book: the case of the Pura Raza Española horse
Perdomo-González, Davinia I.; Laseca, Nora; Demyda-Peyrás, S.; Valera, Mercedes; Cervantes, I.; Molina, Antonio (Springer, 2022)Estimating inbreeding, which is omnipresent and inevitable in livestock populations, is a primary goal for management and animal breeding especially for those interested in mitigating the negative consequences of inbreeding. ... -
Genomic Characterization of Quality Wool Traits in Spanish Merino Sheep
Anaya, Gabriel; Laseca, Nora; Granero, A.; Ziadi, Chiraz; Arrebola, F.; Domingo, A.; Molina Alcalá, Antonio (MDPI, 2024)The native Spanish Merino breed was the founder of all the other Merino and Merino-derived breeds worldwide. Despite the fact that this breed was created and improved to produce the highest quality fine wool, the global ... -
Genomic screening of allelic and genotypic transmission ratio distortion in horse
Laseca, Nora; Cánovas, Ángela; Valera, Mercedes; Id-Lahoucine, Samir; Perdomo-González, Davinia I.; Fonseca, Pablo A. S.; Demyda-Peyrás, S.; Molina, Antonio (Public Library os Science, 2023)The phenomenon in which the expected Mendelian inheritance is altered is known as transmission ratio distortion (TRD). The TRD analysis relies on the study of the transmission of one of the two alleles from a heterozygous ... -
Prevalence of Sex-Related Chromosomal Abnormalities in a Large Cohort of Spanish Purebred Horses
Demyda-Peyrás, S.; Laseca, Nora; Anaya, Gabriel; Kij-Mitka, Barbara; Molina, Antonio; Karlau, Ayelén; Valera Córdoba, M. (MDPI, 2023)Chromosomal abnormalities are largely associated with fertility impairments in the domestic horse. To date, over 600 cases of individuals carrying abnormal chromosome complements have been reported, making the domestic ... -
Quantitative analysis of parent-of-origin effect in reproductive and morphological selection criteria in the Pura Raza Española horse
Perdomo-González, D.I.; Varona, L.; Molina Alcalá, Antonio; Laseca, Nora; Valera, M. (Wiley, 2023)It is generally assumed that parents make a genetically equal contribution to their offspring, but this assumption might not always hold. This is because the expression of a gene can be blocked by methylation during ... -
Reproductive traits in Pura Raza Española mares manifest inbreeding depression from low levels of homozygosity
Laseca, Nora; Ziadi, Chiraz; Perdomo-González, Davinia I.; Valera, Mercedes; Demyda-Peyrás, S.; Molina, Antonio (Wiley, 2023)Inbreeding depression is a genetic phenomenon associated with the loss of fitness and mean phenotypic performance due to mating between relatives. Historically, inbreeding coefficients have been estimated from pedigree ... -
Screening and detection of chromosomal copy number alterations in the domestic horse using SNP-array genotyping data
Pirosanto, Yamila; Laseca, Nora; Valera, Mercedes; Molina, Antonio; Moreno-Millán, M.; Bugno-Poniewierska, M.; Ross, Pablo; Azor, Pedro; Demyda-Peyrás, S. (Wiley, 2021)Chromosomal abnormalities are a common cause of infertility in horses. However, they are difficult to detect using automated methods. Here, we propose a simple methodology based on single nucleotide polymorphism (SNP)-array ...