• Coenzyme Q10 and Cardiovascular Diseases 

      Gutiérrez Mariscal, Francisco Miguel; Cruz‐Ares, Silvia de la; Torres‑Peña, J.D.; Alcalá-Diaz, Juan F.; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2021)
      Coenzyme Q10 (CoQ10), which plays a key role in the electron transport chain by providing an adequate, efficient supply of energy, has another relevant function as an antioxidant, acting in mitochondria, other cell ...
    • Diet and SIRT1 Genotype Interact to Modulate Aging-Related Processes in Patients with Coronary Heart Disease: From the CORDIOPREV Study 

      Hidalgo-Moyano, Cristina; Rangel-Zuñiga, Oriol Alberto; Gómez Delgado, Francisco; Alcalá Díaz, Juan Francisco; Rodríguez-Cantalejo, Fernando; Yubero-Serrano, Elena M.; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Camargo García, A.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2022)
      We investigated whether long-term consumption of two healthy diets (low-fat (LF) or Mediterranean (Med)) interacts with SIRT1 genotypes to modulate aging-related processes such as leucocyte telomere length (LTL), oxidative ...
    • Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations 

      Pérez-Caballero, Ana I.; García-Ríos, Antonio; Gómez-Luna, María J.; Gómez-Luna, Purificación; Dembinska-Kiec, Aldona; Rodríguez-Cantalejo, Fernando; Camargo García, A.; Marín, Carmen; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; Tinahones, Francisco J.; Pérez-Jiménez, Francisco; Roche, Helen M.; López-Miranda, José (Public Library Of Science (PLOS), 2012)
      Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked to higher cardiovascular risk. To date, there is little information about the additional impact of ...
    • Endothelial Aging Associated with Oxidative Stress Can Be Modulated by a Healthy Mediterranean Diet 

      Marín, Carmen; Yubero-Serrano, Elena M.; Pérez-Jiménez, Francisco; López-Miranda, José (MDPI, 2013)
      Aging is a condition which favors the development of atherosclerosis, which has been associated with a breakdown in repair processes that occurs in response to cell damage. The dysregulation of the biological systems ...
    • Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study 

      Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)
      Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ...
    • Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study) 

      Talavera-García, Eva; Delgado-Lista, Javier; García-Ríos, Antonio; Delgado-Casado, Nieves; Gómez-Luna, Purificación; Gómez-Garduño, Ángela; Gómez Delgado, Francisco; Alcalá Díaz, Juan Francisco; Yubero-Serrano, Elena M.; Marín, Carmen; Pérez-Caballero, Ana I.; Fuentes-Jiménez, Francisco J.; Rodríguez-Cantalejo, Fernando; Tinahones, Francisco J.; Ordovás, José María; Pérez-Jiménez, Francisco; Pérez-Martínez, Pablo; López-Miranda, José; Camargo García, A. (Public Library of Science, 2016)
      Background Recent data suggest that the presence of associated metabolic abnormalities may be important modifiers of the association of obesity with a poorer prognosis in coronary heart disease. We determined the influence ...
    • Long-term effect of a dietary intervention with two-healthy dietary approaches on food intake and nutrient density in coronary patients: results from the CORDIOPREV trial 

      Cano‑Ibáñez, Naomi; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; Rangel Zúñiga, Oriol Alberto; Camargo García, A.; Yubero-Serrano, Elena M.; Pérez‑Corral, Isabel; Arenas de Larriva, Antonio P.; García-Ríos, Antonio; Pérez-Martínez, Pablo; Delgado-Lista, Javier; López-Miranda, José (Springer, 2022)
      Background: Cardiovascular disease (CVD) is the leading cause of disease burden in the world by non-communicable diseases. Nutritional interventions promoting high-quality dietary patterns with low caloric intake value and ...
    • Potential Role of Insulin Growth-Factor-Binding Protein 2 as Therapeutic Target for Obesity-Related Insulin Resistance 

      Boughanem, Hatim; Yubero-Serrano, Elena M.; López-Miranda, José; Tinahones, Francisco J.; Macías-González, Manuel (MDPI, 2021)
      Evidence from observational and in vitro studies suggests that insulin growth-factor-binding protein type 2 (IGFBP2) is a promising protein in non-communicable diseases, such as obesity, insulin resistance, metabolic ...
    • Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids 

      Rangel Zúñiga, Oriol Alberto; Camargo García, A.; Marín, Carmen; Peña Orihuela, Judhit; Pérez-Martínez, Pablo; Delgado-Lista, Javier; González Guardia, Lorena; Yubero-Serrano, Elena M.; Tinahones, Francisco J.; Malagón, María M.; Pérez-Jiménez, Francisco; Roche, Helen M.; López-Miranda, José (BioMed Central, 2015)
      Background: Metabolic syndrome is a multi-component disorder associated to a high risk of cardiovascular disease. Its etiology is the result of a complex interaction between genetic and environmental factors, including ...
    • Quality and Quantity of Protein Intake Influence Incidence of Type 2 Diabetes Mellitus in Coronary Heart Disease Patients: From the CORDIOPREV Study 

      Cruz‐Ares, Silvia de la; Gutiérrez Mariscal, Francisco Miguel; Alcalá Díaz, Juan Francisco; Quintana-Navarro, Gracia M.; Podadera-Herreros, Alicia; Cardelo, Magdalena P.; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2021)
      Evidence suggests that enriching a diet with plant-based proteins could reduce the risk of developing type 2 diabetes mellitus. In the present work, we evaluated the association between the change in plant protein intake ...
    • Telomere maintenance is associated with type 2 diabetes remission in response to a long-term dietary intervention without non-weight loss in patients with coronary heart disease: from the CORDIOPREV randomized controlled trial 

      Ojeda-Rodríguez, Ana; Alcalá Díaz, Juan Francisco; Rangel Zúñiga, Oriol Alberto; Arenas de Larriva, Antonio P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; Mora-Ortiz, Marina; Romero-Cabrera, Juan Luis; Luque, Raúl M.; Ordovas, José M.; Pérez-Martínez, Pablo; Delgado-Lista, Javier; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2024)
      In order to evaluate whether telomere maintenance is associated with type 2 diabetes remission, newly diagnosed type 2 diabetes patients without glucose-lowering treatment (183 out of 1002) from the CORDIOPREV study ...