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Analysis of Global and Local DNA Methylation Patterns in Blood Samples of Patients With Autism Spectrum Disorder
García-Ortiz, M.V.; Torre‑Aguilar, M. J. de la; Morales-Ruiz, T.; Gómez Fernández, Antonio Rafael; Flores Rojas, Katherine Ubina; Gil Campos, Mercedes; Martín-Borreguero, Pilar; Ariza, Rafael R.; Roldán-Arjona, Teresa; Pérez Navero, Juan Luis (Frontiers, 2021)The goal of this investigation was to determine whether there are alterations in DNA methylation patterns in children with autism spectrum disorder (ASD). Material and Methods: Controlled prospective observational ... -
Metabolic shift underlies tumor progression and immune evasion in S-nitrosoglutathione reductase-deficient cancer
Mena-Osuna, Rafael; Mantrana, Ana; Guil-Luna, Silvia; Sánchez, María-Teresa; Navarrete, Carmen; Morales-Ruiz, T.; Rivas-Crespo, Aurora; Toledano-Fonseca, Marta; García-Ortíz, María Victoria; García Jurado, Gema; Gómez-España, M. Auxiliadora; González Fernández, Rafael A.; Villar, Carlos; Medina Fernández, Francisco Javier; Villalba, José Manuel; Aranda Aguilar, Enrique; Rodríguez-Ariza, Antonio (Wiley, 2023)S-nitrosoglutathione reductase (GSNOR) is a denitrosylase enzyme that has been suggested to play a tumor suppressor role, although the mechanisms responsible are still largely unclear. In this study, we show that GSNOR ...