Mostrar el registro sencillo del ítem

dc.contributor.authorCaballero-Gómez, Javier
dc.contributor.authorRivero-Juárez, Antonio
dc.contributor.authorJurado-Tarifa, Estefanía
dc.contributor.authorJiménez-Martín, Débora
dc.contributor.authorJiménez-Ruiz, Elena
dc.contributor.authorCastro-Scholten, Sabrina
dc.contributor.authorUlrich, Rainer G.
dc.date.accessioned2023-06-29T11:01:43Z
dc.date.available2023-06-29T11:01:43Z
dc.date.issued2021
dc.identifier.issn1865-1682
dc.identifier.urihttp://hdl.handle.net/10396/25666
dc.description.abstractHepatitis E virus (HEV) is an emerging zoonotic pathogen that is currently recognized as one of themajor causes of acute human hepatitis worldwide. In Europe, the increasing number of hepatitis E cases is mainly associated with the consumption of animal food products or contact with infected animals. Dogs and cats have been suggested as a zoonotic source of HEV infection. The aim of this study was to assess Orthohepevirus circulation, including HEV-A, HEV-B and HEV-C species, in sympatric urban cats and dogs in southern Spain. Between 2017 and 2020, blood samples were collected from 144 stray cats and 152 dogs, both strays and pets. The presence of antibodies againstHEV were tested using a double-antigen sandwich ELISA and seropositive simples were further analysed bywestern blot.ART-PCR was performed to detect RNAof Orthohepevirus species (HEV-A,HEV-B andHEV-C).Atotal of 19 (6.4%; 95%CI: 3.6-9.2) of the 296 animals tested showed anti-HEV antibodies by ELISA. Seropositivity was significantly higher in dogs (9.9%; 15/152; 95%CI: 5.1-14.6) than in cats (2.8%; 4/144; 95%CI: 0.1-5.5). Ten of the 18 ELISA-positive animals that could be further analysed by western blot, reacted against HEV-3 and/or HEV-C1 antigens, which suggest circulation of both genotypes in urban cats and dogs in the study area. However, HEV-A, HEV-B and HEV-C RNA were not detected in any of the tested sera. This is the first study to assess HEV circulation in both stray cats and dogs in Europe. Our results provide evidence of HEV exposure in sympatric urban cat and dog populations in southern Spain. Further studies are needed to determine the role of these species in the epidemiology of HEV.es_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherWileyes_ES
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/es_ES
dc.sourceTransbound Emerg Dis.;69:240–248 (2022)es_ES
dc.subjectCatses_ES
dc.subjectDogses_ES
dc.subjectHepatitis Ees_ES
dc.subjectOrthohepevirus Aes_ES
dc.subjectOrthohepevirus Ces_ES
dc.subjectSurveyes_ES
dc.subjectZoonoseses_ES
dc.titleSerological and molecular survey of hepatitis E virus in cats and dogs in Spaines_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publisherversion10.1111/tbed.14437es_ES
dc.relation.projectIDGobierno de España. RD12/0017/0012
dc.relation.projectIDMinisterio de España. CP18/00111
dc.relation.projectIDMinisterio de España. INT20-00028
dc.relation.projectIDMinisterio de España. FPU17/01319
dc.relation.projectIDMinisterio de España. FPU19/06026;
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


Ficheros en el ítem

Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem