ListarProducción Científica por tema "DNA methylation"
Mostrando ítems 1-11 de 11
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A DNA 3′ Phosphatase Functions in Active DNA Demethylation in Arabidopsis
(Cell Press, 2012)DNA methylation is an important epigenetic mark established by the combined actions of methylation and demethylation reactions. Plants use a base excision repair pathway for active DNA demethylation. After 5-methylcytosine ... -
Active DNA demethylation in plants
(MDPI, 2019)Methylation of cytosine (5-meC) is a critical epigenetic modification in many eukaryotes, and genomic DNA methylation landscapes are dynamically regulated by opposed methylation and demethylation processes. Plants are ... -
An AP Endonuclease Functions in Active DNA Demethylation and Gene Imprinting in Arabidopsis
(Public Library of Science, 2015)Active DNA demethylation in plants occurs through base excision repair, beginning with removal of methylated cytosine by the ROS1/DME subfamily of 5-methylcytosine DNA glycosylases. Active DNA demethylation in animals ... -
An Entropy Approach to Multiple Sclerosis Identification
(MDPI, 2022)Multiple sclerosis (MS) is a relatively common neurodegenerative illness that frequently causes a large level of disability in patients. While its cause is not fully understood, it is likely due to a combination of genetic ... -
Bioinformatic approaches for identification of epigenetic profiles in neuropathology processes
(Universidad de Córdoba, UCOPress, 2022)Degenerative neurological diseases, such as Alzheimer, Multiple Sclerosis or Huntington Disease, are illnesses that are not well-known while at the same time having a significant impact on the quality of life of the ... -
Genetic and epigenetic bases of Quercus ilex variability
(Universidad de Córdoba, UCOPress, 2024)Quercus ilex, the most representative species of the Mediterranean forest and agrosilvopastoral ecosystem “dehesa”, displays remarkable phenotypic variability and plasticity owing to its longevity and allogamous nature. ... -
Neural Network Aided Detection of Huntington Disease
(MDPI, 2022)Huntington Disease (HD) is a degenerative neurological disease that causes a significant impact on the quality of life of the patient and eventually death. In this paper we present an approach to create a biomarker using ... -
Promoter DNA Hypermethylation and Gene Repression in Undifferentiated Arabidopsis Cells
(Public Library of Science, 2008)Maintaining and acquiring the pluripotent cell state in plants is critical to tissue regeneration and vegetative multiplication. Histone-based epigenetic mechanisms are important for regulating this undifferentiated state. ... -
Red and White Wine Lees show inhibitory effects on liver carcinogenesis
(Wiley, 2019-05)Scope: Wine has shown anticarcinogenic benefits in hepatocarcinoma and polyphenols seem to be responsible for these effects. Wine lees are the sediments produced during fermentation and they endow wine with organoleptic ... -
Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosineDNA glycosylase to a sequence-specific DNA binding domain
(Taylor & Francis, 2017)DNA methylation is a crucial epigenetic mark associated to gene silencing, and its targeted removal is amajor goal of epigenetic editing. In animal cells, DNA demethylation involves iterative 5mC oxidation byTET enzymes ... -
The C-terminal domain of Arabidopsis ROS1 DNA demethylase interacts with histone H3 and is required for DNA binding and catalytic activity. DNA Repair
(Elsevier, 2022)La desmetilación activa del ADN desempeña un papel importante en el control de los patrones de metilación en los eucariotas. En las plantas, la familia DEMETER-LIKE (DML) de 5-metilcitosina ADN glicosilasas inicia la ...