• Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin 

      Martins, Luis; Fernández-Mayo, Diana; Novelle, Marta G.; Vázquez, María J.; Nogeiras, Rubén; López, Miguel; Diéguez, Carlos; Tena-Sempere, Manuel (Public Library Of Science (PLOS), 2012)
      Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase ...