Listar DBCFI-Artículos, capítulos... por autor "fc98ec0f-7fea-4873-841e-12f58ca43efe"
Mostrando ítems 21-26 de 26
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Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue
Novelle, Marta G.; Vázquez, María J.; Peinado, Juan R.; Martinello, Kátia D.; López, Miguel; Luckman, Simon M.; Tena-Sempere, Manuel; Malagón, María M.; Nogueiras, Rubén; Diéguez, Carlos (Nature Research, 2017)During their lifetime, females are subjected to different nutritional and hormonal factors that could increase the risk of obesity and associated comorbidities. From early postnatal periods until the postmenopausal phase, ... -
The ghrelin O-acyltransferase–ghrelin system reduces TNF-α-induced apoptosis and autophagy in human visceral adipocytes
Rodríguez, A; Gómez-Ambrosi, Javier; Catalán, Victoria; Rotellar, Fernando; Valentí, Víctor; Silva, Camilo; Mugueta, C.; Pulido, Marina R.; Vázquez, R.; Salvador, Javier; Malagón, María M.; Colina, I.; Frühbeck, Gema (SpringerLink, 2012)Aims/hypothesis Proinflammatory and proapoptotic cytokines such as TNF-α are upregulated in human obesity. We evaluated the association between ghrelin isoforms (acylated and desacyl ghrelin) and TNF-α in obesity and ... -
The l-α-Lysophosphatidylinositol/GPR55 system and its potential role in human obesity
Moreno-Navarrete, José María; Catalán, Victoria; Whyte, Lauren; Díaz-Arteaga, Adenis; Vázquez-Martínez, Rafael; Rotellar, Fernando; Guzmán-Ruiz, Rocío; Gómez-Ambrosi, Javier; Pulido, Marina R.; Russell, Wendy R.; Imbernón, Mónica; Ross, Ruth A.; Malagón, María M.; Diéguez, Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Nogueiras, Rubén (American Diabetes Asociation, 2012)GPR55 is a putative cannabinoid receptor, and l-α-lysophosphatidylinositol (LPI) is its only known endogenous ligand. We investigated 1) whether GPR55 is expressed in fat and liver; 2) the correlation of both GPR55 and LPI ... -
The potential role of the adipokine HMGB1 in obesity and insulin resistance. Novel effects on adipose tissue biology
Guzmán Ruiz, R.; Tercero-Alcázar, C.; López-Alcalá, J.; Sánchez Ceinos, Julia; Malagón, María M.; Gordon, Ana (Elsevier, 2021)Discovery of the adipose tissue as a major source of signaling molecules almost three decades ago set a novel physiological paradigm that paved the way for the identification of metabolic organs as endocrine organs. ... -
The Role of Autophagy in White Adipose Tissue Function: Implications for Metabolic Health
Clemente-Postigo, Mercedes; Tinahones, Alberto; Bekay, Rajaa El; Malagón, María M.; Tinahones, Francisco J. (MDPI, 2020)White adipose tissue (WAT) is a highly adaptive endocrine organ that continuously remodels in response to nutritional cues. WAT expands to store excess energy by increasing adipocyte number and/or size. Failure in WAT ... -
The stromal-vascular fraction of adipose tissue contributes to major differences between subcutaneous and visceral fat depots
Peinado, Juan R.; Jiménez Gómez, Yolanda; Pulido, Marina R.; Ortega-Bellido, María; Díaz-López, César; Padillo, Francisco; López Miranda, José; Vazquez-Martínez, Rafael; Malagón, María M. (Wiley, 2010)Adipose tissue represents a complex tissue both in terms of its cellular composition, as it includes mature adipocytes and the various cell types comprising the stromal-vascular fraction (SVF), and in relation to the ...