• Desarrollo de un modelo docente adaptado a los criterios metodológicos 

      Ruiz, Antonio; Gaytán, Francisco; Lucena, Concepción; Villalba, José Manuel; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Gracia-Navarro, F.; González Reyes, José Antonio; García-Navarro, Socorro; Castaño, Justo P.; Alcaín Tejada, F.J.; Burón, Isabel; Malagón, María M. (Consejo Social de la Universidad de Córdoba, 2008)
    • Endocrinología celular y molecular 

      García Navarro, S.; Ruiz Navarro, A.; Martínez Fuentes, A.J.; Vázquez Martínez, Rafael; Durán Prado, M.; Rodríguez Pacheco, F.; Molina Sánchez, M.; Cruz García, D.; Gutiérrez Pascual, E.; Díaz-Ruiz Ruiz, A.; Gahete Ortiz, Manuel D.; Pulido Toledano, M.; Castaño, Justo P.; Malagón, María M. (Universidad de Córdoba, 2009)
      El correcto funcionamiento y homeostasis del organismo requieren un control de la secreción hormonal, cuyos defectos producen graves desórdenes endocrinos y metabólicos. Esta regulación mediada por la interacción ...
    • Identification of novel genes involved in the plasticity of pituitary melanotropes in amphibians 

      Malagón, María M.; Cruz García, D.; Díaz-Ruiz Ruiz, A.; Peinado, Juan R.; Pulido, Marina R.; Araújo, J.; García Navarro, S.; Gracia-Navarro, F.; Castaño, Justo P.; Vázquez Martínez, Rafael (New York Academy os Sciences, 2009)
      Melanotrope cells from the amphibian intermediate lobe are composed of two subpopulations that exhibit opposite secretory behavior: hypersecretory and hormone-storage hyposecretory melanotropes. Isolation of these ...
    • Journal article resistin regulates pituitary somatotrope cell function through the activation of multiple signaling pathways 

      Rodríguez Pacheco, F.; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Pulido, Marina R.; Gahete Ortiz, Manuel D.; Vaudry, Hubert; Gracia-Navarro, F.; Diéguez, Carlos; Castaño, Justo P.; Malagón, María M. (Endocrine Society, 2009)
      The adipokine resistin is an insulin-antagonizing factor that also plays a regulatory role in inflammation, immunity, food intake, and gonadal function. Although adipose tissue is the primary source of resistin, it is also ...
    • Melanotrope Secretory Cycle is Regulated by Physiological Inputs via the Hypothalamus 

      Vázquez Martínez, Rafael; Castaño, Justo P.; Tonon, Marie Christine; Vaudry, Hubert; Gracia-Navarro, F.; Malagón, María M. (2017-03-17)
      Previously, it has been shown that background color conditions regulate the overall activity of the frog intermediate lobe by varying the proportions of the two subtypes of melanotropes existing in the gland, the highly ...
    • Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue 

      Pulido, Marina R.; Rabanal Ruiz, Yoana; Almabouada, Farid; Díaz-Ruiz, Alberto; Burrel, María A; Vázquez, María J.; Castaño, Justo P.; Kineman, Rhonda D.; Luque, Raúl M.; Diéguez, Carlos; Vázquez-Martínez, Rafael; Malagón, María M. (Society for Endocrinology, 2013)
      There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...
    • Proteomic profiling of adipose tissue from Zmpste24(-/-) Mice, a model of Lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing 

      Peinado, Juan R.; Moral Quirós, Pedro; Pulido, Marina R.; Mariño García, Guillermo; Martínez-Chantar, M.L.; Vázquez Martínez, Rafael; Pérez Freije, José María; López Ontín, Carlos; Malagón, María M. (Science Direct, 2011)
      Lipodystrophy is a major disease involving severe alterations of adipose tissue distribution and metabolism. Mutations in genes encoding the nuclear envelope protein lamin A or its processing enzyme, the metalloproteinase ...
    • Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity 

      Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García Navarro, S.; Gracia-Navarro, F.; Tinahones, Francisco J.; López-Miranda, José; Frühbeck, Gema; Vázquez Martínez, Rafael; Malagón, María M. (PLOS, 2011)
      Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...
    • Rab18 is reduced in pituitary tumors cusing acromegaly and its overexpression reverts growth hormone hypersecretion 

      Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Pulido, Marina R.; Jiménez Reina, L.; Quintero, Ana; Leal-Cerro, Alfonso; Soto, Alfonso; Webb, Susan M.; Sucunza, Nuria; Bartumeus, Frederic; Benito-López, Pedro; Galvez-Moreno, María A.; Castaño, Justo P.; Malagón, María M. (Oxford Academic, 2008)
      Context: Rab proteins regulate the sequential steps of intracellular membrane transport. Alterations of these GTPases and their associated proteins are emerging as the underlying cause for several human diseases involving ...
    • The l-α-Lysophosphatidylinositol/GPR55 system and its potential role in human obesity 

      Moreno-Navarrete, José María; Catalán, Victoria; Whyte, Lauren; Díaz-Arteaga, Adenis; Vázquez-Martínez, Rafael; Rotellar, Fernando; Guzmán-Ruiz, Rocío; Gómez-Ambrosi, Javier; Pulido, Marina R.; Russell, Wendy R.; Imbernón, Mónica; Ross, Ruth A.; Malagón, María M.; Diéguez, Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Nogueiras, Rubén (American Diabetes Asociation, 2012)
      GPR55 is a putative cannabinoid receptor, and l-α-lysophosphatidylinositol (LPI) is its only known endogenous ligand. We investigated 1) whether GPR55 is expressed in fat and liver; 2) the correlation of both GPR55 and LPI ...
    • Uso de mandos interactivos de respuesta como base para la mejora de la docencia en los Grados impartidos en la Facultad de Ciencias 

      Pérez-Vicente, C.; Siles López, José Ángel; Ruiz Roldán, Carmen; Martínez-Fuentes, Antonio J.; García-Ortiz, M.V.; Martín-Romero, M.T.; Bárcena Ruiz, José Antonio; Padilla Peña, Carmen Alicia; Márquez Espinosa, Ramiro; Vázquez Martínez, Rafael; Díaz Soriano, Antonio Manuel; Marinas, Alberto; Delgado Marzo, Juan Manuel; López Toledano, Azahara; Pérez-Morales, M.; Miguel, Gustavo de (UCOPress, 2017)
      La implantación de los nuevos Grados dentro del EEES supone un nuevo enfoque metodológico, pero sobre todo evaluador. El profesor debe esforzarse en ser capaz de valorar no sólo el nivel de conocimientos del alumnado sobre ...