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Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
(Public Library Of Science (PLOS), 2012)
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation
of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase ...
Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue
(Nature Research, 2017)
During their lifetime, females are subjected to different nutritional and hormonal factors that could increase the risk of obesity and associated comorbidities. From early postnatal periods until the postmenopausal phase, ...