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The Somatostatin Analogue Octreotide Inhibits Growth of Small Intestine Neuroendocrine Tumour Cells
(Public Library Of Science (PLOS), 2012)
Octreotide is a widely used synthetic somatostatin analogue that significantly improves the management of
neuroendocrine tumours (NETs). Octreotide acts through somatostatin receptors (SSTRs). However, the molecular
mechanisms ...
Role of Endogenous Cortistatin in the Regulation of Ghrelin System Expression at Pancreatic Level under Normal and Obese Conditions
(Public Library Of Science (PLOS), 2013)
Ghrelin-system components [native ghrelin, In1-ghrelin, Ghrelin-O-acyltransferase enzyme (GOAT) and receptors (GHS-Rs)]
are expressed in a wide variety of tissues, including the pancreas, where they exert different ...