Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 131-150 de 286
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Identification of new kinase substrates involved in the DNA Damage Response pathway and its implication in carcinogenesis
(Universidad de Córdoba, UCOPress, 2017)One of the most relevant altered pathways in cancer is the DNA Damage Response (DDR), a well-coordinated network of signalling cascades that cells have developed during evolution in order to maintain genomic integrity. ... -
Identification of novel biomarkers and therapeutic targets in the pathological interaction between the dysregulation of the endocrinemetabolic system and prostate cancer
(Universidad de Córdoba, UCOPress, 2022)Obesity (OB) is a metabolic chronic disease with a growing incidence and elevated morbidities and mortality [1, 2]. OB is also associated with elevated economic costs for the health systems representing a worldwide public ... -
Identification of novel cellular and/or molecular markers involved in the pharmacological response and contributions of splicing mechanisms in pituitary tumors
(Universidad de Córdoba, UCOPress, 2019) -
Identification of novel clinical and molecular factors for the diagnosis and aggressiveness of prostate cancer
(Universidad de Córdoba, UCOPress, 2019)Prostate cancer (PCa) is the most common solid neoplasm in men in developed countries. Unfortunately, the extraordinary heterogeneity and complexity of PCa, together with its phenotypic/clinical variability, strongly ... -
Identification of novel endocrine-metabolic and splicing machinery factors with diagnostic, prognostic and/or therapeutic potential in prostate cancer
(Universidad de Córdoba, UCOPress, 2020)Prostate cancer (PCa) is the tumor pathology with the highest incidence among men in developed countries and represents one of the main causes of cancer-related death in this group. Despite the advances achieved during the ... -
Identification of novel genes involved in the plasticity of pituitary melanotropes in amphibians
(New York Academy os Sciences, 2009)Melanotrope cells from the amphibian intermediate lobe are composed of two subpopulations that exhibit opposite secretory behavior: hypersecretory and hormone-storage hyposecretory melanotropes. Isolation of these ... -
Identification of Novel Markers and Molecular Mechanisms with Diagnostic, Prognostic, and Therapeutic Potential in Brain Tumors
(Universidad de Córdoba, UCOPress, 2022)Primary brain tumors represent a highly variable and heterogeneous group of neoplasms (~150 different types) that includes non-malignant and malignant tumors. The most frequent malignant brain tumors are gliomas (representing ... -
Identification of novel molecular markers and contribution of splicing mechanisms in endocrine-related tumoral pathologies
(Universidad de Córdoba, UCOPress, 2020)Cancer represents one of the main challenges for the human being, in that it encompasses some of the most severe and health-threatening pathologies worldwide. Although great efforts are being implemented and significant ... -
Identification of novel molecular markers in pituitary tumors: contribution to pathogenesis and therapeutic potential
(Universidad de Córdoba, UCOPress, 2015)Los adenomas hipofisarios se han considerado comúnmente como una patología tumoral infrecuente debido, posiblemente, a una subestimación en su diagnóstico y consecuentemente, baja incidencia; sin embargo, resultados de ... -
Identification of potential bioactive peptides in sheep milk kefir through peptidomic analysis at different fermentation times
(MDPI, 2023)Sheep farming is an important socioeconomic activity in most Mediterranean countries, particularly Spain, where it contributes added value to rural areas. Sheep milk is used in Spain mainly for making cheese, but it can ... -
Immune Checkpoint Inhibitors for Vaccine Improvements: Current Status and New Approaches
(MDPI, 2022)In recent years, the use of immune checkpoint inhibitors (ICIs) in combination with approved or experimental vaccines has proven to be a promising approach to improve vaccine immunogenicity and efficacy. This strategy seeks ... -
Immunohistochemical analysis of ß3 integrin (CD61): expression in pig tissues and human tumors
(Fundación Séneca, 2002)CD61 is a membrane glycoprotein that associates with CD41 (aIIb) to form the heterodimeric complex gpIIb/IIIa (CD41/CD61), predominantly expressed in platelets and megakariocytes. CD61 or ß3 integrin also associates ... -
Immunomodulatory and Inhibitory Effect of Immulina®, and Immunloges® in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses
(MDPI, 2018)Immulina®, a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis (Spirulina) is a potent activator of innate immune cells. On the other hand, it is well documented that Spirulina ... -
Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review
(MDPI, 2024)Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and ... -
Impacto de la capacidad de fijación C1Q de los anticuerpos preformados específicos de donante sobre la evolución del aloinjerto renal
(Universidad de Córdoba, UCOPress, 2018)Introducción. La consolidación del ensayo single antigen beads (SABpanIgG) como método para la detección de anticuerpos frente a antígenos leucocitarios humanos (HLA), sin duda ha mejorado las expectativas de éxito en ... -
Implicación activa del alumnado en el sistema de evaluación continua en el aula
(Consejo Social de la Universidad de Córdoba, 2010) -
Implicación de las características clínico-patológicas, radiológicas y marcadores moleculares en el tratamiento de la acromegalia
(Universidad de Córdoba, UCOPress, 2021)La acromegalia se debe a la producción excesiva de hormona del crecimiento (GH), generalmente por un adenoma hipofisario. El tratamiento primario de elección es el quirúrgico, con unos índices de remisión del 80-90% en ... -
Implication of the alternative splicing process in the development of hepatocelular carcinoma
(Universidad de Córdoba, UCOPress, 2021)Liver cancer represents a complex and heterogeneous pathology that encompasses several types of malignant tumors with unfavorable characteristics and prognosis, including hepatocellular carcinoma or hepatocarcinoma (HCC). ... -
In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features
(Nature.com, 2015)Pituitary adenomas comprise a heterogeneous subset of pathologies causing serious comorbidities, which would benefit from identification of novel, common molecular/cellular biomarkers and therapeutic targets. The ghrelin ... -
Indicación de búsqueda de donante emparentado para el transplante de médula ósea
(Universidad de Córdoba, Servicio de Publicaciones, 2011)En el trasplante de progenitores hematopoyéticos si no hay un hermano HLA idéntico es mejor opción iniciar una búsqueda familiar ampliada que en los registros internacionales. Sin embargo, ésta no es posible sin conocer ...