Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 30-49 de 289
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Beef from Calves Finished with a Diet Based on Concentrate Rich in Agro-Industrial By-Products: Acceptability and Quality Label Preferences in Spanish Meat Consumers
(MDPI, 2021)Conjoint analysis was used to estimate the relative importance of some of the main extrinsic attributes and quality labels of beef in three Spanish cities (Córdoba, Marbella, and Santa Pola) in a study performed with 300 ... -
Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial
(Elsevier, 2021)In order to assess whether previous hepatic IR (Hepatic-IR fasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose- lowering treatment, newly-diagnosed type 2 diabetes ... -
Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2
(Springer, 2021)Huntington’s disease (HD) is a neurodegenerative disorder characterized by unwanted choreatic movements, behavioral and psychiatric disturbances, and dementia. The activation of the hypoxic response pathway through the ... -
Biología molecular del virus de la Hepatitis C en la toma de decisiones clínicas
(Universidad de Córdoba, UCOPress, 2018)The search for markers that can predict this natural history of the disease facilitates clinical decision making. The identification of genetic markers facilitates the management of the information, due to they are markers ... -
Biosíntesis de coenzima Q: mantenimiento de la homeostasis redx y adaptación metabólica
(Universidad de Córdoba, Servicio de Publicaciones, 2010)El coenzima Q es el único lípido antioxidante endógenamente sintetizado en todos los organismos eucariotas. Se localiza en las membranas celulares formando parte de la cadena de transporte de electrones y fosforilación ... -
Cannabidiol and Other Cannabinoids in Demyelinating Diseases
(MDPI, 2021)A growing body of preclinical evidence indicates that certain cannabinoids, including cannabidiol (CBD) and synthetic derivatives, may play a role in the myelinating processes and are promising small molecules to be developed ... -
Caracterización celular y molecular de la proteina neuroendocrine long coiled-coil 2 (NECC2)
(Universidad de Córdoba, Servicio de Publicaciones, 2011)Como se mencionó en la introducción del presente trabajo, estudios previos en nuestro grupo de investigación permitieron la identificación de una nueva proteína long coiled-coil específica de vertebrados a partir de un ... -
Caracterización de alteraciones metabólicas y reproductoras en modelos de manipulación nutricional y gonadal aplicada en diversas etapas del desarrollo: impacto de la obesidad sobre el eje reproductor
(Universidad de Córdoba, Servicio de Publicaciones, 2014)1. Introducción o motivación de la tesis Actualmente, la obesidad es la enfermedad metabólica más frecuente en los países desarrollados, estando asociada a la aparición de otras morbilidades, como resistencia a insulina, ... -
Caracterización de las conexiones intracelulares que definen la expansión disfuncional del tejido adiposo en obesidad
(Universidad de Córdoba, UCOPress, 2024)El tejido adiposo desempeña un papel esencial en la gestión de las reservas energéticas del organismo. Los adipocitos son las células más abundantes del tejido adiposo y constituyen su unidad funcional. Están especializados ... -
Caracterización de nuevas rutas reguladoras del metabolismo lipídico en adipocitos. Alteraciones en obesidad
(Universidad de Córdoba, UCOPress, 2020) -
Caracterización de nuevos marcadores reguladores del funcionamiento del tejido adiposo
(Universidad de Córdoba, UCOPress, 2017)El tejido adiposo blanco constituye un depósito de energía altamente dinámico, que almacena el exceso de energía en períodos de balance energético positivo y los moviliza en períodos de demanda energética (Ducharme y Bickel, ... -
Caracterización del papel del sistema NKB/NK3R en el control de la función reproductora
(Universidad de Córdoba, UCOPress, 2019) -
CCN2 Binds to Tubular Epithelial Cells in the Kidney
(MDPI, 2022)Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ... -
Ceruloplasmin and Coronary Heart Disease-A Systematic Review
(MDPI, 2020)Several studies indicate that oxidative stress might play a central role in the initiation and maintenance of cardiovascular diseases. It remains unclear whether ceruloplasmin acts as a passive marker of inflammation or ... -
Changes in quantity plant‑based protein intake on type 2 diabetes remission in coronary heart disease patients: from the CORDIOPREV study
(Springer, 2023)Purpose: Diabetes remission is a phenomenon described in the context of drastic weight loss due to bariatric surgery or low-calorie diets. Evidence suggests that increasing the intake of plant protein could reduce the risk ... -
Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study
(Elsevier, 2018)Background: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, ... -
Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia
(MDPI, 2020)Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ... -
Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes
(MDPI, 2021)Aims and methods: The aim of this monocentric retrospective observational study was to evaluate the 18-month safety and effectiveness of GLP-1 receptor agonist (GLP-1 RA) dulaglutide (DU) 1.5 mg/once weekly as an add-on ... -
Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer
(MDPI, 2019)Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ... -
CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
(Public Library of Science, 2014)Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in ...