Evaluation of the COBAS TaqMan 48 Real-Time PCR System for Quantitation of Hepatitis B Virus DNA

dc.contributor.author	Gordillo, Rafael M.
dc.contributor.author	Gutiérrez-Aroca, Juan-Bautista
dc.contributor.author	Casal Román, Manuel
dc.date.accessioned	2018-12-19T13:22:57Z
dc.date.available	2018-12-19T13:22:57Z
dc.date.issued	2005
dc.identifier.uri	http://hdl.handle.net/10396/17599
dc.description.abstract	The purpose of this study is to evaluate the usefulness of the new real-time PCR COBAS TaqMan 48 analyzer, comparing it to the existing COBAS AMPLICOR HBV MONITOR based on conventional PCR technology. The study used 104 samples from different patients. No differences were found in the sensitivity of the tests. There was an excellent correlation between the sample with a viral load within the dynamic range of the two tests (r = 0.938). The COBAS TaqMan test has a wider linear range, and this fact enables quantifying of the viral load without diluting the sample.	es_ES
dc.format.mimetype	application/pdf	es_ES
dc.language.iso	eng	es_ES
dc.publisher	American Society for Microbilogy	es_ES
dc.rights	https://creativecommons.org/licenses/by-nc-nd/4.0/	es_ES
dc.source	Journal of Clinical Microbiology 43 (7), 3504-3507 (2005)	es_ES
dc.subject	PCR COBAS	es_ES
dc.subject	Virology	es_ES
dc.title	Evaluation of the COBAS TaqMan 48 Real-Time PCR System for Quantitation of Hepatitis B Virus DNA	es_ES
dc.type	info:eu-repo/semantics/article	es_ES
dc.relation.publisherversion	https://doi.org/10.1128/JCM.43.7.3504-3507.2005	es_ES
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es_ES