• Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications 

      Aurilio, Gaetano; Cimadamore, Alessia; Mazzucchelli, Roberta; López-Beltrán, Antonio; Verri, Elena; Scarpelli, Marina; Massari, Francesco; Cheng, Liang; Santoni, Matteo; Montironi, Rodolfo (MDPI, 2020)
      Around 80–90% of prostate cancer (PCa) cases are dependent on androgens at initial diagnosis; hence, androgen ablation therapy directed toward a reduction in serum androgens and the inhibition of androgen receptor (AR) is ...
    • New Frontiers in Prostate Cancer Treatment: Are We Ready for Drug Combinations with Novel Agents? 

      Aurilio, Gaetano; Cimadamore, Alessia; Santoni, Matteo; Nolé, Franco; Scarpelli, Marina; Massari, Francesco; López-Beltrán, Antonio; Cheng, Liang; Montironi, Rodolfo (MDPI, 2020)
      Medical treatment for metastatic castration-resistant prostate cancer (mCRPC) patients has progressively been evolving from a nonspecific clinical approach to genomics-oriented therapies. The scientific community is in ...
    • Recent Advances in Liquid Biopsy in Patients With Castration Resistant Prostate Cancer 

      Di Nunno, Vincenzo; Gatto, Lidia; Santoni, Matteo; Cimadamore, Alessia; López-Beltrán, Antonio; Cheng, Liang; Scarpelli, Marina; Montironi, Rodolfo; Massari, Francesco (Frontiers, 2018)
      Management of localized and advanced prostate cancer benefits from several therapeutic options with a surprising improvement in terms of clinical outcome. The selection of patients more likely to benefit from a specific ...
    • The Human Microbiota and Prostate Cancer: Friend or Foe? 

      Massari, Francesco; Mollica, Veronica; Di Nunno, Vincenzo; Gatto, Lidia; Santoni, Matteo; Scarpelli, Marina; Cimadamore, Alessia; López-Beltrán, Antonio; Cheng, Liang; Battelli, Nicola; Montinori, Rodolfo; Brandi, Giovanni (MDPI, 2019)
      The human microbiome is gaining increasing attention in the medical community, as knowledge on its role not only in health but also in disease development and response to therapies is expanding. Furthermore, the connection ...