• An Entropy Approach to Multiple Sclerosis Identification 

      Alfonso Pérez, Gerardo; Caballero-Villarraso, Javier (MDPI, 2022)
      Multiple sclerosis (MS) is a relatively common neurodegenerative illness that frequently causes a large level of disability in patients. While its cause is not fully understood, it is likely due to a combination of genetic ...
    • Extra-Virgin Olive Oil Modifies the Changes Induced in Non-Nervous Organs and Tissues by Experimental Autoimmune Encephalomyelitis Models 

      Conde, Cristina; Escribano, Begoña M.; Luque, Evelio; Feijóo, Montserrat; Caballero-Villarraso, Javier; Valdelvira, Manuel E.; Ochoa Sepúlveda, Juan J.; Lillo, Rafael; Paz, Elier; Santamaría, Abel; Agüera, Eduardo; Túnez, Isaac (MDPI, 2019)
      This study reveals the existence of oxidative stress (reactive oxygen species (ROS)) in non-nervous organs and tissues in multiple sclerosis (MS) by means of a model of experimental autoimmune encephalomyelitis (EAE) in ...
    • Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review 

      Gómez-Melero, Sara; Caballero-Villarraso, Javier; Escribano, Begoña M.; Galvao-Carmona, Alejandro; Túnez, Isaac; Agüera Morales, Eduardo (MDPI, 2024)
      Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and ...
    • Neuroprotective effect of S-allyl cysteine on an experimental model of multiple sclerosis: Antioxidant effects 

      Escribano, Begoña M.; Agüera Carmona, Eduardo; Aguilar-Luque, Macarena; Luque, Evelio; Feijóo, Montserrat; Latorre, Manuel; Giraldo, Ana I.; Galván-Jurado, A.; Caballero-Villarraso, Javier; García-Maceira, Fé I.; Santamaría, Abel; Túnez, Isaac (Elsevier, 2018)
      S-allyl cysteine (SAC), has shown itself to performance important activity as a neuroprotective agent. This action is prompted by antioxidative activity. The aim of this study was to evaluate the neuroprotective effect of ...
    • The protective effect of extra-virgin olive oil in the experimental model of multiple sclerosis in the rat 

      Conde, Cristina; Escribano, Begoña M.; Luque, Evelio; Aguilar-Luque, Macarena; Feijoo, Marisa; Ochoa, J.J.; Latorre, Manuel; Giraldo, Ana I.; Lillo, Rafael; Agüera Carmona, Eduardo; Santamaría, Abel; Túnez, Isaac (Taylor & Francis, 2018)
      This study has evaluated the effect of EVOO (Extra-Virgin olive oil), OA (oleic acid) and HT (hydroxytyrosol) in an induced model of MS through experimental autoimmune encephalomyelitis (EAE). Dark Agouti 2-month old ...
    • Transcranial Magnetic Stimulation Improves Muscle Involvement in Experimental Autoimmune Encephalomyelitis 

      Peña-Toledo, María Ángeles; Luque, Evelio; Ruz‐Caracuel, Ignacio; Agüera, Eduardo; Jimena Medina, Ignacio; Peña Amaro, J.; Túnez, Isaac (MDPI, 2021)
      Skeletal muscle is affected in experimental autoimmune encephalomyelitis (EAE), which is a model of multiple sclerosis that produces changes including muscle atrophy; histological features of neurogenic involvement, and ...