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Chlamydomonas reinhardtii—A reference microorganism for Eukaryotic Molybdenum metabolism
(MDPI, 2023)
Molybdenum (Mo) is vital for the activity of a small but essential group of enzymes called molybdoenzymes. So far, specifically five molybdoenzymes have been discovered in eukaryotes: nitrate reductase, sulfite oxidase, ...
Non-specific inhibition of dipeptidyl peptidases 8/9 by dipeptidyl peptidase 4 inhibitors negatively affects mesenchymal stem cell differentiation
(MDPI, 2023)
DPP4 may play a relevant role in MSC differentiation into osteoblasts or adipocytes. Dipeptidyl peptidase 4 (DPP4) inhibitors (DPP4i), such as sitagliptin and vildagliptin, are used as antidiabetic drugs. However, vildagliptin ...
EHO-85, novel amorphous antioxidant hydrogel, containing Olea europaea leaf extract—rheological properties, and superiority over a standard hydrogel in accelerating early wound healing: a randomized controlled trial
(MDPI, 2023)
Many advanced wound healing dressings exist, but there is little high-quality evidence to support them. To determine the performance of a novel amorphous hydrogel (EHO-85) in relation to its application, we compared its ...
CCR6 as a potential target for therapeutic antibodies for the treatment of inflammatory diseases
(MDPI, 2023)
The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide range of biological processes. When CCR6 binds to its sole ligand CCL20, a signaling network is produced. This pathway is implicated ...
Cyanide biodegradation by a native bacterial consortium and its potential for goldmine tailing biotreatment
(MDPI, 2023)
A native cyanide-degrading bacterial consortium was isolated from goldmine tailing sediments. Mine tailings are toxic effluents due to their metal–cyanide complexes. The bacterial consortium was able to degrade an initial ...
Spanish HCMV Seroprevalence in the 21st Century
(MDPI, 2024)
Human cytomegalovirus (HCMV) is linked to age-related diseases like cardiovascular disease, neurodegenerative conditions, and cancer. It can also cause congenital defects and severe illness in immunocompromised individuals. ...
Alterations in oxidative responses and post-translational modification caused by p,p´-DDE in Mus spretus testes reveal Cys oxidation status in proteins related to cell-redox homeostasis and male fertility
(Elsevier, 2018)
The major derivate of DDT, 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene (p,p´-DDE), is a persistent pollutant previously associated with oxidative stress. Additionally, p,p´-DDE has been linked to several metabolic ...
Proteomic profile of the skin mucus of farmed gilthead seabream (Sparus aurata)
(Elsevier, 2015)
Fish skin mucus is the first line of defense against infections and it discriminates between pathogenic and commensal bacterial strains. Mucus composition varies amongst fish species and is influenced by endogenous and ...
Filago pyramidata tolerant to ALS-inhibiting herbicides: a new invasive weed in olive groves
(MDPI, 2023)
Weeds that usually grow in non-agricultural areas have become increasingly common invading perennial crops. Species of the genus Filago, in addition to invading Spanish olive groves, have developed certain levels of natural ...
‘Omics’ approaches for crop improvement
(MDPI, 2023)
The growing human population and climate change are imposing unprecedented challenges on the global food supply [1]. To cope with these pressures, crop improvement demands enhancing important agronomical traits beyond ...