Listar DMed-Artículos, capítulos... por fecha de publicación
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Glucokinase Regulatory Protein Genetic Variant Interacts with Omega-3 PUFA to Influence Insulin Resistance and Inflammation in Metabolic Syndrome
(Public Library Of Science (PLOS), 2011)Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism. Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose ... -
Influencia de la fuerza muscular isométrica de las extremidades superiores en el estrés oxidativo en niños
(Ramón Cantó Alcaraz, 2011)El ejercicio físico puede producir estrés oxidativo en el individuo lo que pueden condicionar el riesgo cardiovascular en niños y adolescentes. Este estudio pretende analizar el estrés oxidativo según la fuerza muscular ... -
Effects of rs7903146 Variation in the Tcf7l2 Gene in the Lipid Metabolism of Three Different Populations
(Public Library Of Science (PLOS), 2012)Background: TCF7L2 rs7903146 is an important genetic factor predicting type 2 diabetes (T2DM) which has also been linked to higher cardiovascular risk. To date, there is little information about the additional impact of ... -
Nuclear Translocation of b-Catenin during Mesenchymal Stem Cells Differentiation into Hepatocytes Is Associated with a Tumoral Phenotype
(Public Libray of Science (PLOS), 2012)Wnt/b-catenin pathway controls biochemical processes related to cell differentiation. In committed cells the alteration of this pathway has been associated with tumors as hepatocellular carcinoma or hepatoblastoma. The ... -
Epidemiologic Behavior of Obesity in the Maracaibo City Metabolic Syndrome Prevalence Study
(Public Libray of Science (PLOS), 2012)Introduction: Obesity is a worldwide public health issue. Since the epidemiological behaviour of this disease is not well established in our country, the purpose of this study was to determinate its prevalence in the ... -
In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/β-catenin activation
(American Journal of Physiology, 2012)The present study investigates the differential effect of two vitamin D receptor agonists, calcitriol and paricalcitol, on human aortic smooth muscle cells calcification in vitro. Human vascular smooth muscle cells were ... -
Informe sobre el aborto
(2012-02-07) -
Método de obtención de datos útiles para predecir la respuesta al tratamiento de la Hepatitis C
(Oficina de Transferencia de Resultados de la Investigación, 2013)La presente invención proporciona un método de obtención de datos útiles para predecir cual será la respuesta de un paciente al tratamiento de la hepatitis C, específicamente al tratamiento con interferón pegilado y ... -
NUTRITECH
(Oficina de Transferencia de Resultados de la Investigación, 2013)NutriTech is a European Commission funded FP7 research project (2012-2015) The goal of NutriTech is to quantify the effect of diet on “phenotypic flexibility”. Phenotypic flexibility extends on metabolic flexibility (the ... -
Endothelial Aging Associated with Oxidative Stress Can Be Modulated by a Healthy Mediterranean Diet
(MDPI, 2013)Aging is a condition which favors the development of atherosclerosis, which has been associated with a breakdown in repair processes that occurs in response to cell damage. The dysregulation of the biological systems ... -
Chromosomal numeric abnormalities on early bovine embryos derived from in vitro fertilization: effect of the oocyte quality, maturation environment and incubation time
(CSIRO Publishing, 2013)Chromosomal aberrations are one of the major causes of embryo failures in the mammals. It is also been demonstrated that the occurrence of this kind of abnormalities is higher on in vitro produced (IVP) embryos. This study ... -
Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells
(Public Library of Science, 2014)Magnesium reduces vascular smooth muscle cell (VSMC) calcification in vitro but the mechanism has not been revealed so far. This work used only slightly increased magnesium levels and aimed at determining: a) whether ... -
TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
(Public Library of Science, 2014)Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ... -
Hypertriglyceridemia Influences the Degree of Postprandial Lipemic Response in Patients with Metabolic Syndrome and Coronary Artery Disease: From the Cordioprev Study
(PLOS, 2014)Objective To determine whether metabolic syndrome traits influence the postprandial lipemia response of coronary patients, and whether this influence depends on the number of MetS criteria. Materials and Methods 1002 ... -
Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids
(BioMed Central, 2015)Background: Metabolic syndrome is a multi-component disorder associated to a high risk of cardiovascular disease. Its etiology is the result of a complex interaction between genetic and environmental factors, including ... -
Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
(Public Library of Science, 2016)Background Recent data suggest that the presence of associated metabolic abnormalities may be important modifiers of the association of obesity with a poorer prognosis in coronary heart disease. We determined the influence ... -
Impact of the Content of Fatty Acids of Oral Fat Tolerance Tests on Postprandial Triglyceridemia: Systematic Review and Meta-Analysis
(MDPI, 2016)Whether the content of saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA) could differently influence postprandial triglycerides (TG) is unknown. We examined possible differences in the ... -
Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study
(BioMed Central, 2016)Background/aims: Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, ... -
Educación sanitaria a los estudiantes de Grado en Educación Infantil y Grado en Educación Primaria en el manejo del niño alérgico en la escuela
(UCOPress, 2018)La alergia en edad pediátrica es un problema de salud pública emergente y a su vez complejo de abordar. A pesar de esto, apenas hay protocolos de identificación de alumnos alérgicos y tampoco se incluyen en los planes ... -
Magnesium Replacement to Protect Cardiovascular and Kidney Damage? Lack of Prospective Clinical Trials
(MDPI, 2018)Patients with advanced chronic kidney disease exhibit an increase in cardiovascular mortality. Recent works have shown that low levels of magnesium are associated with increased cardiovascular and all-cause mortality in ...